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  2. Htr5a - 5-hydroxytryptamine (serotonin) receptor 5A Gene

Htr5a - 5-hydroxytryptamine (serotonin) receptor 5A Gene

中文名称:5-羟色胺 (血清素) 受体 5A

种属: Mus musculus

同用名: Htr5

基因 ID: 15563 | 基因类型: protein coding

关于 Htr5a

Chromosome 5: 28,047,147-28,060,086 forward strand.GRCm39:CM000998.3

This gene has 1 transcript (splice variant), 215 orthologues, 9 paralogues and is associated with 3 phenotypes. Biased expression in cortex adult (RPKM 2.1), frontal lobe adult (RPKM 2.) and 4 other tissues.

功能概要

预测该基因编码的蛋白编码的蛋白可启动 G 蛋白偶联血清素受体活性;神经递质受体活性;和血清素结合活性。作用于腺苷酸环化酶激活 G 蛋白偶联受体信号通路的上游或内部。预测位于高尔基体;核周;和粗面内质网。预计在树突中活跃。预计是质膜的组成部分。以多种结构表达,包括脂肪组织;脑;眼睛;女性生殖系统;和直觉。与人 HTR5A(5-羟色胺受体 5A)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable G protein-coupled serotonin receptor activity; neurotransmitter receptor activity; and serotonin binding activity. Acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in Golgi apparatus; perikaryon; and rough endoplasmic reticulum. Predicted to be active in dendrite. Predicted to be integral component of plasma membrane. Is expressed in several structures, including adipose tissue; brain; eye; female reproductive system; and gut. Orthologous to human HTR5A (5-hydroxytryptamine receptor 5A). [provided by Alliance of Genome Resources, Apr 2022]

Htr5a 基因产物(1)

mRNA Protein Name
NM_008314.2 NP_032340.2 5-hydroxytryptamine receptor 5A
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
11406289 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Htr5a 蛋白结构

7tm_GPCRs

7tm_GPCRs: cl28897 (40 - 348)

7tm_GPCRs

7tm_GPCRs: cd14964 (42 - 66)

7tm_GPCRs

7tm_GPCRs: cd14964 (75 - 97)

7tm_GPCRs

7tm_GPCRs: cd14964 (114 - 136)

7tm_GPCRs

7tm_GPCRs: cd14964 (159 - 175)

7tm_GPCRs

7tm_GPCRs: cd14964 (197 - 220)

7tm_GPCRs

7tm_GPCRs: cd14964 (283 - 305)

7tm_GPCRs

7tm_GPCRs: cd14964 (316 - 341)

  • 0
  • 100
  • 200
  • 300
  • 357 a.a.
蛋白主名 其他名称

5-hydroxytryptamine receptor 5A

5-HT-5

5-HT-5A

5-HT5A

serotonin receptor 5A

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Htr5a NCBI NCBI:3361