2. Gene
  3. Iapp - islet amyloid polypeptide Gene

Iapp - islet amyloid polypeptide Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: DAP

基因 ID: 15874 | 基因类型: protein coding

关于 Iapp

功能概要

Predicted to enable identical protein binding activity. Acts upstream of or within negative regulation of bone resorption; negative regulation of cell differentiation; and sensory perception of pain. Located in extracellular space and neuronal cell body. Is expressed in embryo; pancreas; pancreas primordium; and pancreas trunk epithelium. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus and type 2 diabetes mellitus. Orthologous to human IAPP (islet amyloid polypeptide). [provided by Alliance of Genome Resources, Apr 2022]

Iapp 基因产物(1)

mRNA Protein Name
NM_010491.2 NP_034621.1 islet amyloid polypeptide precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of bone resorption IMP
IMP: 通过突变表型推断
14970190 MGI
acts upstream of or within negative regulation of bone resorption IMP
IMP: 通过突变表型推断
14970190 MGI
acts upstream of or within negative regulation of osteoclast differentiation IGI
IGI: 通过遗传相互作用推断
14970190 MGI
acts upstream of or within negative regulation of osteoclast differentiation IMP
IMP: 通过突变表型推断
14970190 MGI
acts upstream of osteoclast differentiation IGI
IGI: 通过遗传相互作用推断
14970190 MGI
acts upstream of osteoclast differentiation IMP
IMP: 通过突变表型推断
14970190 MGI
acts upstream of or within sensory perception of pain IMP
IMP: 通过突变表型推断
9838101 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
17693256 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

islet amyloid polypeptide

amylin

diabetes-associated peptide

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P1871A Amylin (IAPP), feline TFA 98.75% 否
HY-P1871 Amylin (IAPP), feline / 否
HY-P3926 Amylin (8-37) (human) / 否
HY-P4767 Amylin (1-13) (human) Ligand / 否
HY-RS06506 IAPP Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17689 Iapp Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24151 Iapp Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Iapp NCBI NCBI:3375
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