1. Gene
  2. Ier3 - immediate early response 3 Gene

Ier3 - immediate early response 3 Gene

种属: Mus musculus

同用名: cI-3; IEX-1; gly96

基因 ID: 15937 | 基因类型: protein coding

关于 Ier3

功能概要

Acts upstream of or within several processes, including intracellular signal transduction; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; and regulation of nucleobase-containing compound metabolic process. Located in nucleus. Is expressed in brain; head; and placenta. Orthologous to human IER3 (immediate early response 3). [provided by Alliance of Genome Resources, Apr 2022]

Ier3 基因产物(1)

mRNA Protein Name
NM_133662.2 NP_598423.1 radiation-inducible immediate-early gene IEX-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19096392 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within DNA damage response IMP
IMP: 通过突变表型推断
20467439 MGI
acts upstream of glycolytic process IMP
IMP: 通过突变表型推断
19096392 MGI
acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage IDA
IDA: 通过直接分析推断
11753682 MGI
acts upstream of or within mitotic G2 DNA damage checkpoint signaling IMP
IMP: 通过突变表型推断
20467439 MGI
acts upstream of or within negative regulation of glycolytic process IMP
IMP: 通过突变表型推断
19096392 MGI
acts upstream of or within negative regulation of inflammatory response IMP
IMP: 通过突变表型推断
19923449 MGI
acts upstream of or within negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway IDA
IDA: 通过直接分析推断
19096392 MGI
acts upstream of or within negative regulation of systemic arterial blood pressure IMP
IMP: 通过突变表型推断
16166241 MGI
acts upstream of or within positive regulation of protein catabolic process IDA
IDA: 通过直接分析推断
19096392 MGI
acts upstream of or within regulation of DNA repair IMP
IMP: 通过突变表型推断
20467439 MGI
acts upstream of or within regulation of nucleocytoplasmic transport IMP
IMP: 通过突变表型推断
20467439 MGI
acts upstream of or within regulation of reactive oxygen species metabolic process IDA
IDA: 通过直接分析推断
19096392 MGI
acts upstream of or within response to protozoan IMP
IMP: 通过突变表型推断
19923449 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
20467439 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

radiation-inducible immediate-early gene IEX-1

cAMP inducible gene 3

immediate early protein GLY96

immediate early response 3 protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ier3 NCBI NCBI:8870