SLC5A12 - solute carrier family 5 member 12 Gene

中文名称：溶质载体家族 5 成员 12

种属: Homo sapiens

同用名: SMCT2

关于 SLC5A12

功能概要

正常血乳酸维持在 1.5 mM 左右，过滤后的乳酸很少从尿液中排出。乳酸的重吸收由近端小管初始部分的低亲和力 Na (+) 偶联乳酸转运蛋白 SLC5A12 和远端近端的高亲和力 Na (+) 偶联乳酸转运蛋白 SLC5A8 (MIM 608044) 介导小管 (Gopal 等人，2007 [PubMed 17692818]) 。[OMIM 提供，2008 年 12 月]

Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed 17692818]).[supplied by OMIM, Dec 2008]