Igf2r - insulin-like growth factor 2 receptor Gene

种属: Mus musculus

同用名: CD222; CI-MPR; Mpr300; M6P/IGF2R

关于 Igf2r

功能概要

Enables insulin-like growth factor binding activity and mannose binding activity. Predicted to be involved in several processes, including liver development; positive regulation by host of viral process; and response to retinoic acid. Located in membrane and nuclear envelope lumen. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; early conceptus; and genitourinary system. Human ortholog(s) of this gene implicated in diabetes mellitus (multiple); hepatocellular carcinoma; in situ carcinoma (multiple); and nephroblastoma. Orthologous to human IGF2R (Insulin like growth factor 2 receptor). [provided by Alliance of Genome Resources, Apr 2022]