1. Gene
  2. CLEC14A - C-type lectin domain containing 14A Gene

CLEC14A - C-type lectin domain containing 14A Gene

中文名称:含 C 型凝集素结构域 14A

种属: Homo sapiens

同用名: CEG1; EGFR-5; C14orf27

基因 ID: 161198 | 基因类型: protein coding

关于 CLEC14A

Cytogenetic location: 14q21.1 Genomic coordinates (GRCh38): 14:38,254,000-38,256,093 (from NCBI)

This gene has 1 transcript (splice variant), 288 orthologues and 8 paralogues.


该基因编码 C 型凝集素/C 型凝集素样结构域 (CTL/CTLD) 超家族的成员。该家族的成员具有共同的蛋白质折叠并具有多种功能,例如细胞粘附、细胞间信号传导、糖蛋白转换以及在炎症和免疫反应中的作用。该家族成员在细胞间粘附和血管生成中发挥作用。它在丝状伪足形成、细胞迁移和管形成中起作用。由于其在肿瘤内皮中的含量高于正常组织内皮中的含量,因此被认为是肿瘤血管靶向的候选药物。[RefSeq 提供,2012 年 1 月]

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting. [provided by RefSeq, Jan 2012]

CLEC14A 基因产物(1)

mRNA Protein Name
NM_175060.3 NP_778230.1 C-type lectin domain family 14 member A precursor
蛋白主名 其他名称

C-type lectin domain family 14 member A

ClECT and EGF-like domain containing protein

重组 CLEC14A 蛋白

目录号 产品名 蛋白编号 纯度
HY-P700693 CLEC14A Protein, Human (HEK293, His) Q86T13 (E22-A397) ≥95%


种属 基因名 来源 基因 ID
Bos taurus CLEC14A VGNC VGNC:27425
Mus musculus CLEC14A MGD MGI:1914114
Macaca mulatta CLEC14A VGNC VGNC:108292
Rattus norvegicus CLEC14A RGD RGD:1306232
Canis familiaris CLEC14A VGNC VGNC:39327
Felis catus CLEC14A VGNC VGNC:60943