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  2. Inhba - inhibin beta-A Gene

Inhba - inhibin beta-A Gene

种属: Mus musculus

基因 ID: 16323 | 基因类型: protein coding

关于 Inhba

功能概要

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Homozygous knockout mice for this gene lack whiskers and exhibit tooth and palate defects, leading to neonatal lethality. [provided by RefSeq, Aug 2016]

Inhba 基因产物(1)

mRNA Protein Name
NM_008380.2 NP_032406.1 inhibin beta A chain preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
1646080 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Sertoli cell differentiation IMP
IMP: 通过突变表型推断
32274496 MGI
acts upstream of or within androgen metabolic process IMP
IMP: 通过突变表型推断
32274496 MGI
acts upstream of or within androst-4-ene-3,17-dione biosynthetic process IMP
IMP: 通过突变表型推断
32954300 MGI
involved in eyelid development in camera-type eye IGI
IGI: 通过遗传相互作用推断
14551263 MGI
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
32274496 MGI
acts upstream of or within hematopoietic progenitor cell differentiation IDA
IDA: 通过直接分析推断
7799920 MGI
acts upstream of or within lipid metabolic process IMP
IMP: 通过突变表型推断
32274496 MGI
acts upstream of or within male gonad development IMP
IMP: 通过突变表型推断
32274496 MGI
acts upstream of or within mesoderm formation IDA
IDA: 通过直接分析推断
7799920 MGI
acts upstream of or within mesodermal cell differentiation IDA
IDA: 通过直接分析推断
7799920 MGI
involved in positive regulation of DNA-templated transcription IGI
IGI: 通过遗传相互作用推断
14551263 MGI
involved in positive regulation of ovulation IMP
IMP: 通过突变表型推断
17609433 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
10391928 MGI
acts upstream of or within steroid biosynthetic process IMP
IMP: 通过突变表型推断
32954300 MGI
acts upstream of or within steroid metabolic process IMP
IMP: 通过突变表型推断
32274496 MGI
acts upstream of or within testosterone biosynthetic process IMP
IMP: 通过突变表型推断
32274496 MGI
acts upstream of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
10391928 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
8133077 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

inhibin beta A chain

activin A

activin beta-A chain

重组 Inhba 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73241 Activin A Protein, Human/Mouse/Rat (HEK293, His) Q3UY39/NP_032406.1 (S21-S424) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Inhba NCBI NCBI:3624
Rattus norvegicus Inhba NCBI NCBI:29200