2. Gene
  3. Itgal - integrin alpha L Gene

Itgal - integrin alpha L Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Cd11a; LFA-1; Ly-15; Ly-21; (p180); LFA-1A

基因 ID: 16408 | 基因类型: protein coding

关于 Itgal

功能概要

Predicted to enable ICAM-3 receptor activity and cell adhesion molecule binding activity. Involved in cell-cell adhesion. Acts upstream of or within several processes, including activated T cell proliferation; positive regulation of T cell proliferation; and positive regulation of calcium-mediated signaling. Located in cell-cell junction; external side of plasma membrane; and immunological synapse. Is expressed in heart; hemolymphoid system; and vault of skull. Orthologous to human ITGAL (Integrin subunit alpha L). [provided by Alliance of Genome Resources, Apr 2022]

Itgal 基因产物(4)

mRNA Protein Name
NM_001253872.1 NP_001240801.1 integrin alpha-L isoform 1 precursor
NM_001253873.1 NP_001240802.1 integrin alpha-L isoform 3 precursor
NM_001253874.1 NP_001240803.1 integrin alpha-L isoform 4 precursor
NM_008400.3 NP_032426.2 integrin alpha-L isoform 2 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within activated T cell proliferation IMP
IMP: 通过突变表型推断
15210787 MGI
acts upstream of calcium-mediated signaling IDA
IDA: 通过直接分析推断
8117278 MGI
acts upstream of or within cell surface receptor signaling pathway IDA
IDA: 通过直接分析推断
8117278 MGI
involved in cell-cell adhesion IGI
IGI: 通过遗传相互作用推断
12652296 MGI
acts upstream of or within leukocyte cell-cell adhesion IDA
IDA: 通过直接分析推断
8117278 MGI
acts upstream of or within leukocyte cell-cell adhesion IMP
IMP: 通过突变表型推断
8562500 MGI
acts upstream of or within positive regulation of T cell proliferation IMP
IMP: 通过突变表型推断
1346270 MGI
acts upstream of or within positive regulation of calcium-mediated signaling IDA
IDA: 通过直接分析推断
8117278 MGI
acts upstream of or within positive regulation of cell-cell adhesion IMP
IMP: 通过突变表型推断
1346270 MGI
acts upstream of or within regulation of cell-cell adhesion IDA
IDA: 通过直接分析推断
8117278 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell-cell junction IDA
IDA: 通过直接分析推断
23793062 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
8043862 MGI
located in immunological synapse IDA
IDA: 通过直接分析推断
15064761 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

integrin alpha-L

CD11 antigen-like family member A

alpha L integrin

leukocyte adhesion glycoprotein LFA-1 alpha chain

leukocyte function-associated molecule 1 alpha chain

lymphocyte antigen 15

lymphocyte function associated antigen 1, alpha polypeptide

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06959 ITGAL Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20429 Itgal Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26938 Itgal Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Itgal NCBI NCBI:3683
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