2. Gene
  3. Itgb5 - integrin beta 5 Gene

Itgb5 - integrin beta 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: [b]5; [b]-5; [b]5A; [b]5B; beta5; ESTM23; beta-5

基因 ID: 16419 | 基因类型: protein coding

关于 Itgb5

功能概要

Enables Integrin binding activity. Involved in integrin-mediated signaling pathway; stress fiber assembly; and transforming growth factor beta receptor signaling pathway. Located in cell leading edge; focal adhesion; and glutamatergic synapse. Is integral component of synaptic membrane. Part of Integrin alphav-beta5 complex. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; embryo mesenchyme; and genitourinary system. Orthologous to human ITGB5 (Integrin subunit beta 5). [provided by Alliance of Genome Resources, Apr 2022]

Itgb5 基因产物(3)

mRNA Protein Name
NM_001145884.2 NP_001139356.1 integrin beta-5 isoform 1 precursor
NM_001405063.1 NP_001391992.1 integrin beta-5 isoform 3
NM_010580.3 NP_034710.2 integrin beta-5 isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables integrin binding IPI
IPI: 通过物理相互作用推断
8601592 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
24997346 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in integrin-mediated signaling pathway IMP
IMP: 通过突变表型推断
24036928 MGI
involved in stress fiber assembly IMP
IMP: 通过突变表型推断
24036928 MGI
involved in transforming growth factor beta receptor signaling pathway IMP
IMP: 通过突变表型推断
24036928 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell leading edge IDA
IDA: 通过直接分析推断
18794329 MGI
located in focal adhesion IDA
IDA: 通过直接分析推断
18794329 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
16467530 MGI
is active in glutamatergic synapse IEP
IEP: 通过表达模式推断
16467530 MGI
part of integrin alphav-beta5 complex IDA
IDA: 通过直接分析推断
20826760 MGI
is active in synaptic membrane IDA
IDA: 通过直接分析推断
16467530 MGI
is active in synaptic membrane IEP
IEP: 通过表达模式推断
16467530 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

integrin beta-5

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06969 ITGB5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18068 Itgb5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24543 Itgb5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Itgb5 NCBI NCBI:3693
Macaca fascicularis Itgb5 NCBI NCBI:102123619
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