2. Gene
  3. Itm2b - integral membrane protein 2B Gene

Itm2b - integral membrane protein 2B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Bri; Bri2; E25BMM; imBRI2; Bricd2b; D14Sel6

基因 ID: 16432 | 基因类型: protein coding

关于 Itm2b

功能概要

Enables ATP binding activity. Acts upstream of or within extrinsic apoptotic signaling pathway in absence of ligand. Predicted to be located in Golgi-associated vesicle membrane and extracellular space. Predicted to be integral component of organelle membrane. Predicted to be active in Golgi apparatus and plasma membrane. Is expressed in central nervous system; pancreas epithelium; and retina. Used to study cerebral amyloid angiopathy. Human ortholog(s) of this gene implicated in ITM2B-related cerebral amyloid angiopathy 1 and ITM2B-related cerebral amyloid angiopathy 2. Orthologous to human ITM2B (integral membrane protein 2B). [provided by Alliance of Genome Resources, Apr 2022]

Itm2b 基因产物(1)

mRNA Protein Name
NM_008410.3 NP_032436.1 integral membrane protein 2B precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
10679242 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
20945367 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

integral membrane protein 2B

immature BRI2

integral membrane protein 2B (E25B protein)

transmembrane protein BRI

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06984 ITM2B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21603 Itm2b Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Itm2b NCBI NCBI:9445
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