1. Gene
  2. Kcnc3 - potassium voltage gated channel, Shaw-related subfamily, member 3 Gene

Kcnc3 - potassium voltage gated channel, Shaw-related subfamily, member 3 Gene

种属: Mus musculus

同用名: Kv3.3; Kcr2-3; KShIIID

基因 ID: 16504 | 基因类型: protein coding

关于 Kcnc3

功能概要

Predicted to enable delayed rectifier Potassium Channel activity. Acts upstream of or within regulation of neurotransmitter secretion. Located in several cellular components, including neuromuscular junction; neuron projection membrane; and neuronal cell body membrane. Is expressed in aortic valve; arch of aorta; brain; descending thoracic aorta; and thoracic aorta. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 13. Orthologous to human KCNC3 (potassium voltage-gated channel subfamily C member 3). [provided by Alliance of Genome Resources, Apr 2022]

Kcnc3 基因产物(15)

mRNA Protein Name
NM_001290682.2 NP_001277611.1 potassium voltage-gated channel subfamily C member 3 isoform 2
NM_001385625.1 NP_001372554.1 potassium voltage-gated channel subfamily C member 3 isoform 3
NM_001385626.1 NP_001372555.1 potassium voltage-gated channel subfamily C member 3 isoform 4
NM_001385627.1 NP_001372556.1 potassium voltage-gated channel subfamily C member 3 isoform 5
NM_001385628.1 NP_001372557.1 potassium voltage-gated channel subfamily C member 3 isoform 6
NM_001385629.1 NP_001372558.1 potassium voltage-gated channel subfamily C member 3 isoform 7
NM_001385630.1 NP_001372559.1 potassium voltage-gated channel subfamily C member 3 isoform 7
NM_001385631.1 NP_001372560.1 potassium voltage-gated channel subfamily C member 3 isoform 2
NM_001385632.1 NP_001372561.1 potassium voltage-gated channel subfamily C member 3 isoform 8
NM_001385633.1 NP_001372562.1 potassium voltage-gated channel subfamily C member 3 isoform 8
NM_001385634.1 NP_001372563.1 potassium voltage-gated channel subfamily C member 3 isoform 9
NM_001385635.1 NP_001372564.1 potassium voltage-gated channel subfamily C member 3 isoform 10
NM_001385636.1 NP_001372565.1 potassium voltage-gated channel subfamily C member 3 isoform 11
NM_001385637.1 NP_001372566.1 potassium voltage-gated channel subfamily C member 3 isoform 12
NM_008422.3 NP_032448.2 potassium voltage-gated channel subfamily C member 3 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables voltage-gated potassium channel activity IDA
IDA: 通过直接分析推断
15217387 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within regulation of neurotransmitter secretion IMP
IMP: 通过突变表型推断
15610163 MGI
involved in regulation of synaptic vesicle endocytosis IDA
IDA: 通过直接分析推断
33508244 MGI
involved in regulation of synaptic vesicle endocytosis IMP
IMP: 通过突变表型推断
33508244 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axolemma IDA
IDA: 通过直接分析推断
18682278 MGI
located in axon terminus IDA
IDA: 通过直接分析推断
15610163 MGI
is active in calyx of Held IDA
IDA: 通过直接分析推断
33508244 MGI
is active in calyx of Held IMP
IMP: 通过突变表型推断
33508244 MGI
located in dendrite IDA
IDA: 通过直接分析推断
15217387 MGI
located in dendrite membrane IDA
IDA: 通过直接分析推断
18682278 MGI
located in neuromuscular junction IDA
IDA: 通过直接分析推断
15610163 MGI
located in neuronal cell body membrane IDA
IDA: 通过直接分析推断
18682278 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

potassium voltage-gated channel subfamily C member 3

voltage-gated potassium channel subunit Kv3.3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kcnc3 NCBI NCBI:3748