2. Gene
  3. Kcnd2 - potassium voltage-gated channel, Shal-related family, member 2 Gene

Kcnd2 - potassium voltage-gated channel, Shal-related family, member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Kv4.2

基因 ID: 16508 | 基因类型: protein coding

关于 Kcnd2

功能概要

Enables A-type (transient outward) Potassium Channel activity and voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential. Involved in several processes, including locomotor rhythm; neuronal action potential; and potassium ion transmembrane transport. Acts upstream of or within action potential. Located in several cellular components, including GABA-ergic synapse; dendritic spine; and postsynaptic membrane. Is integral component of postsynaptic membrane. Part of voltage-gated Potassium Channel complex. Is active in glutamatergic synapse. Is integral component of postsynaptic specialization membrane. Is expressed in several structures, including heart; hindlimb digit; metanephros; nervous system; and sensory organ. Orthologous to human KCND2 (potassium voltage-gated channel subfamily D member 2). [provided by Alliance of Genome Resources, Apr 2022]

Kcnd2 基因产物(1)

mRNA Protein Name
NM_019697.4 NP_062671.1 potassium voltage-gated channel subfamily D member 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables A-type (transient outward) potassium channel activity IDA
IDA: 通过直接分析推断
9734479 MGI
enables A-type (transient outward) potassium channel activity IMP
IMP: 通过突变表型推断
18045912 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15662035 MGI
enables voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IDA
IDA: 通过直接分析推断
17582333 MGI
enables voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IMP
IMP: 通过突变表型推断
17582333 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in locomotor rhythm IMP
IMP: 通过突变表型推断
22815518 MGI
acts upstream of or within neuronal action potential IMP
IMP: 通过突变表型推断
20573902 MGI
involved in neuronal action potential IMP
IMP: 通过突变表型推断
22815518 MGI
involved in potassium ion transmembrane transport IDA
IDA: 通过直接分析推断
9734479 MGI
involved in potassium ion transmembrane transport IMP
IMP: 通过突变表型推断
18045912 MGI
involved in sensory perception of pain IMP
IMP: 通过突变表型推断
18045912 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
17122053 MGI
located in dendrite IDA
IDA: 通过直接分析推断
11040264 MGI
located in dendritic spine IDA
IDA: 通过直接分析推断
21943606 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
17122053 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
17582333 MGI
located in membrane IDA
IDA: 通过直接分析推断
18603586 MGI
located in neuronal cell body IDA
IDA: 通过直接分析推断
11040264 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
9734479 MGI
is active in postsynaptic membrane IDA
IDA: 通过直接分析推断
17122053 MGI
is active in postsynaptic specialization membrane IDA
IDA: 通过直接分析推断
17122053 MGI
part of voltage-gated potassium channel complex IDA
IDA: 通过直接分析推断
19713751 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

potassium voltage-gated channel subfamily D member 2

voltage-gated potassium channel subunit Kv4.2

Kcnd2 抗体

目录号 产品名 应用 反应物种
HY-P86936 Kv4.2/KCND2 Antibody (YA6629) IHC-F, IHC-P, WB Mouse, Rat

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07113 KCND2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21609 Kcnd2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kcnd2 NCBI NCBI:3751
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