2. Gene
  3. Kif3a - kinesin family member 3A Gene

Kif3a - kinesin family member 3A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Kif3; Kifl; Kns3

基因 ID: 16568 | 基因类型: protein coding

关于 Kif3a

功能概要

Enables intraciliary transport particle B binding activity and microtubule binding activity. Involved in centriole-centriole cohesion and microtubule anchoring at centrosome. Acts upstream of or within several processes, including animal organ development; chordate embryonic development; and plasma membrane bounded cell projection organization. Located in centriole; motile cilium; and photoreceptor connecting cilium. Part of Kinesin II complex. Is expressed in several structures, including gonad; liver; neural tube; node; and spleen. Used to study dysostosis and polycystic kidney disease. Orthologous to human KIF3A (Kinesin family member 3A). [provided by Alliance of Genome Resources, Apr 2022]

Kif3a 基因产物(3)

mRNA Protein Name
NM_001290805.1 NP_001277734.1 kinesin-like protein KIF3A isoform 2
NM_001290806.1 NP_001277735.1 kinesin-like protein KIF3A isoform 3
NM_008443.4 NP_032469.2 kinesin-like protein KIF3A isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables intraciliary transport particle B binding IDA
IDA: 通过直接分析推断
12821668 MGI
enables microtubule binding IDA
IDA: 通过直接分析推断
17360631 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12821668 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in alpha-tubulin acetylation IMP
IMP: 通过突变表型推断
27793670 MGI
acts upstream of or within anterior/posterior pattern specification IMP
IMP: 通过突变表型推断
10220415 MGI
involved in anterograde dendritic transport EXP
EXP: 通过实验结果推断
26335646 MGI
involved in anterograde dendritic transport IDA
IDA: 通过直接分析推断
26335646 MGI
involved in anterograde dendritic transport IEP
IEP: 通过表达模式推断
26335646 MGI
involved in anterograde dendritic transport IMP
IMP: 通过突变表型推断
26335646 MGI
involved in anterograde dendritic transport of neurotransmitter receptor complex IDA
IDA: 通过直接分析推断
31746486 MGI
involved in anterograde dendritic transport of neurotransmitter receptor complex IMP
IMP: 通过突变表型推断
31746486 MGI
involved in centriole-centriole cohesion IMP
IMP: 通过突变表型推断
23386061 MGI
acts upstream of or within cilium assembly IMP
IMP: 通过突变表型推断
10220415 MGI
involved in cilium assembly IMP
IMP: 通过突变表型推断
21209331 MGI
acts upstream of or within cilium movement IMP
IMP: 通过突变表型推断
29891944 MGI
acts upstream of or within dentate gyrus development IMP
IMP: 通过突变表型推断
18297065 MGI
acts upstream of or within determination of left/right symmetry IMP
IMP: 通过突变表型推断
10220415 MGI
acts upstream of or within dorsal/ventral neural tube patterning IGI
IGI: 通过遗传相互作用推断
18590716 MGI
acts upstream of or within dorsal/ventral neural tube patterning IMP
IMP: 通过突变表型推断
18590716 MGI
involved in dorsal/ventral neural tube patterning IMP
IMP: 通过突变表型推断
21209331 MGI
acts upstream of or within dorsal/ventral pattern formation IMP
IMP: 通过突变表型推断
15755804 MGI
acts upstream of or within epidermal stem cell homeostasis IMP
IMP: 通过突变表型推断
21429982 MGI
acts upstream of or within epidermis development IMP
IMP: 通过突变表型推断
21703454 MGI
acts upstream of or within forebrain development IMP
IMP: 通过突变表型推断
28291836 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
18729223 MGI
acts upstream of or within heart looping IMP
IMP: 通过突变表型推断
10330409 MGI
acts upstream of or within in utero embryonic development IGI
IGI: 通过遗传相互作用推断
19286674 MGI
acts upstream of or within inner ear receptor cell stereocilium organization IMP
IMP: 通过突变表型推断
18066062 MGI
acts upstream of keratinocyte proliferation IMP
IMP: 通过突变表型推断
21703454 MGI
acts upstream of or within kidney development IMP
IMP: 通过突变表型推断
15067314 MGI
involved in microtubule anchoring at centrosome IMP
IMP: 通过突变表型推断
23386061 MGI
acts upstream of or within motile cilium assembly IMP
IMP: 通过突变表型推断
10330409 MGI
acts upstream of or within neural precursor cell proliferation IMP
IMP: 通过突变表型推断
18297065 MGI
acts upstream of or within neural tube development IMP
IMP: 通过突变表型推断
10330409 MGI
acts upstream of or within non-motile cilium assembly IMP
IMP: 通过突变表型推断
18297065 MGI
acts upstream of or within positive regulation of epithelial cell proliferation IMP
IMP: 通过突变表型推断
21703454 MGI
acts upstream of or within positive regulation of keratinocyte proliferation IMP
IMP: 通过突变表型推断
21703454 MGI
acts upstream of or within smoothened signaling pathway IMP
IMP: 通过突变表型推断
18297065 MGI
involved in smoothened signaling pathway IMP
IMP: 通过突变表型推断
27793670 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in centriole IDA
IDA: 通过直接分析推断
23386061 MGI
located in cilium IDA
IDA: 通过直接分析推断
17825299 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
31746486 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
31746486 MGI
part of kinesin II complex IDA
IDA: 通过直接分析推断
19384852 MGI
located in motile cilium IDA
IDA: 通过直接分析推断
10330409 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
17360631 MGI
located in photoreceptor connecting cilium IDA
IDA: 通过直接分析推断
19208653 MGI
is active in postsynapse EXP
EXP: 通过实验结果推断
26335646 MGI
is active in postsynapse IDA
IDA: 通过直接分析推断
26335646 MGI
is active in postsynapse IEP
IEP: 通过表达模式推断
26335646 MGI
is active in postsynapse IMP
IMP: 通过突变表型推断
26335646 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

kinesin-like protein KIF3A

N-4 kinesin

kinesin-II subunit

microtubule plus end-directed kinesin motor 3A

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07285 KIF3A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22595 Kif3a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29112 Kif3a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kif3a NCBI NCBI:11127
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