1. Gene
  2. Kif7 - kinesin family member 7 Gene

Kif7 - kinesin family member 7 Gene

种属: Mus musculus

基因 ID: 16576 | 基因类型: protein coding

关于 Kif7

功能概要

Enables identical protein binding activity. Involved in negative regulation of smoothened signaling pathway and positive regulation of smoothened signaling pathway. Acts upstream of or within aorta development; cardiac septum development; and coronary vasculature development. Located in ciliary basal body. Is expressed in metanephros and testis. Used to study acrocallosal syndrome; ciliopathy; congenital diaphragmatic hernia; and hydrolethalus syndrome. Human ortholog(s) of this gene implicated in acrocallosal syndrome; cleft lip; and hydrolethalus syndrome 2. Orthologous to human KIF7 (Kinesin family member 7). [provided by Alliance of Genome Resources, Apr 2022]

Kif7 基因产物(4)

mRNA Protein Name
NM_001291222.2 NP_001278151.1 kinesin-like protein KIF7 isoform 1
NM_001412613.1 NP_001399542.1 kinesin-like protein KIF7 isoform 3
NM_001412614.1 NP_001399543.1 kinesin-like protein KIF7 isoform 4
NM_010626.3 NP_034756.2 kinesin-like protein KIF7 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
24952464 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
19549984 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within aorta development IMP
IMP: 通过突变表型推断
25807483 MGI
acts upstream of or within cardiac septum development IMP
IMP: 通过突变表型推断
25807483 MGI
acts upstream of or within coronary vasculature development IMP
IMP: 通过突变表型推断
25807483 MGI
involved in negative regulation of smoothened signaling pathway IMP
IMP: 通过突变表型推断
19549984 MGI
involved in positive regulation of smoothened signaling pathway IMP
IMP: 通过突变表型推断
19549984 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in ciliary basal body IDA
IDA: 通过直接分析推断
25644602 MGI
located in ciliary tip IDA
IDA: 通过直接分析推断
29038301 MGI
located in cilium IDA
IDA: 通过直接分析推断
19666503 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

kinesin-like protein KIF7

kinesin 7

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kif7 NCBI NCBI:374654