1. Gene
  2. Krt14 - keratin 14 Gene

Krt14 - keratin 14 Gene

种属: Mus musculus

同用名: K14; CK-14; Krt1-14; Krt-1.14

基因 ID: 16664 | 基因类型: protein coding

关于 Krt14

功能概要

This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the Cytoskeleton of epithelial cells. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

Krt14 基因产物(3)

mRNA Protein Name
NM_001313956.1 NP_001300885.1 keratin, type I cytoskeletal 14 isoform 2
NM_001313957.1 NP_001300886.1 keratin, type I cytoskeletal 14 isoform 3
NM_016958.2 NP_058654.1 keratin, type I cytoskeletal 14 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11408584 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within keratinocyte differentiation IDA
IDA: 通过直接分析推断
19303854 MGI
acts upstream of or within response to radiation IDA
IDA: 通过直接分析推断
30305288 MGI
acts upstream of or within stem cell differentiation IDA
IDA: 通过直接分析推断
19303854 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basal part of cell IDA
IDA: 通过直接分析推断
23599337 MGI
located in cell periphery IDA
IDA: 通过直接分析推断
11698679 MGI
is active in cornified envelope IDA
IDA: 通过直接分析推断
26644517 MGI
located in intracellular anatomical structure IDA
IDA: 通过直接分析推断
16489008 MGI
located in keratin filament IDA
IDA: 通过直接分析推断
14673151 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

keratin, type I cytoskeletal 14

cytokeratin 14

keratin complex 1, acidic, gene 14

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Krt14 NCBI NCBI:3861