1. Gene
  2. MIER3 - MIER family member 3 Gene

MIER3 - MIER family member 3 Gene

中文名称:MIER 家族成员 3

种属: Homo sapiens

基因 ID: 166968 | 基因类型: protein coding

关于 MIER3

Cytogenetic location: 5q11.2 Genomic coordinates (GRCh38): 5:56,919,603-56,952,209 (from NCBI)

This gene has 11 transcripts (splice variants), 236 orthologues and 5 paralogues. Ubiquitous expression in colon (RPKM 18.3), duodenum (RPKM 12.6) and 25 other tissues.

功能概要

预测可启用组蛋白脱乙酰酶结合活性和转录辅阻遏物活性。预计参与 RNA 聚合酶 II 对转录的负调控。位于核质中。部分含蛋白质复合物。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable histone deacetylase binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

MIER3 基因产物(3)

mRNA Protein Name
NM_001297598.2 NP_001284527.1 mesoderm induction early response protein 3 isoform 1
NM_001297599.2 NP_001284528.1 mesoderm induction early response protein 3 isoform 2
NM_152622.5 NP_689835.3 mesoderm induction early response protein 3 isoform 3
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
NOT contributes to histone deacetylase activity IDA
IDA: 通过直接分析推断
28046085 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
28046085 GOA
part of protein-containing complex IDA
IDA: 通过直接分析推断
28046085 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

MIER3 蛋白结构

ELM2

ELM2: ELM2 domain (176 - 224)

  • 0
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  • 200
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  • 400
  • 500
  • 550 a.a.
蛋白主名 其他名称

mesoderm induction early response protein 3

mesoderm induction early response 1, family member 3

直系同源

种属 基因名 来源 基因 ID
Canis familiaris MIER3 VGNC VGNC:43231
Rattus norvegicus MIER3 RGD RGD:1311241
Bos taurus MIER3 VGNC VGNC:31471
Macaca mulatta MIER3 VGNC VGNC:74836
Mus musculus MIER3 MGD MGI:2442317
Felis catus MIER3 VGNC VGNC:63502