2. Gene
  3. Dsg4 - desmoglein 4 Gene

Dsg4 - desmoglein 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: lah; CDHF13

基因 ID: 16769 | 基因类型: protein coding

关于 Dsg4

功能概要

This gene encodes a member of the Cadherin family of proteins that forms an integral transmembrane component of desmosomes, the multiprotein complexes involved in cell adhesion, organization of the Cytoskeleton, cell sorting and cell signaling. This gene is expressed in the suprabasal epidermis and hair follicle. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. Certain mutations in this gene are responsible for the lanceolate hair phenotype in mice. This gene is located in a cluster of desmosomal Cadherin genes on chromosome 18. [provided by RefSeq, Feb 2016]

Dsg4 基因产物(1)

mRNA Protein Name
NM_181564.3 NP_853543.1 desmoglein-4 preproprotein
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within BMP signaling pathway IDA
IDA: 通过直接分析推断
18692037 MGI
acts upstream of or within anagen IMP
IMP: 通过突变表型推断
12705872 MGI
acts upstream of or within cell-cell adhesion IMP
IMP: 通过突变表型推断
12705872 MGI
acts upstream of or within hair follicle development IDA
IDA: 通过直接分析推断
18692037 MGI
acts upstream of or within keratinocyte differentiation IMP
IMP: 通过突变表型推断
12705872 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in desmosome IMP
IMP: 通过突变表型推断
12705872 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

desmoglein-4

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04024 DSG4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19127 Dsg4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25617 Dsg4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dsg4 NCBI NCBI:147409
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