1. Gene
  2. Laptm5 - lysosomal-associated protein transmembrane 5 Gene

Laptm5 - lysosomal-associated protein transmembrane 5 Gene

种属: Mus musculus

同用名: E3; Stra13

基因 ID: 16792 | 基因类型: protein coding

关于 Laptm5

功能概要

Enables enzyme binding activity and protein sequestering activity. Involved in several processes, including lysosomal transport; positive regulation of macromolecule metabolic process; and regulation of signal transduction. Acts upstream of or within cellular response to Leukemia Inhibitory Factor. Located in lysosome. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and liver and biliary system. Orthologous to human LAPTM5 (lysosomal protein transmembrane 5). [provided by Alliance of Genome Resources, Apr 2022]

Laptm5 基因产物(1)

mRNA Protein Name
NM_010686.4 NP_034816.1 lysosomal-associated transmembrane protein 5
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables enzyme binding IPI
IPI: 通过物理相互作用推断
22733818 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18619870 MGI
enables protein sequestering activity IMP
IMP: 通过突变表型推断
18619870 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Golgi to lysosome transport IDA
IDA: 通过直接分析推断
24638062 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
involved in intracellular protein transport IMP
IMP: 通过突变表型推断
31545469 MGI
involved in negative regulation of B cell activation IMP
IMP: 通过突变表型推断
20519653 MGI
involved in negative regulation of T cell activation IMP
IMP: 通过突变表型推断
18619870 MGI
involved in negative regulation of T cell receptor signaling pathway IMP
IMP: 通过突变表型推断
18619870 MGI
involved in negative regulation of activated T cell proliferation IMP
IMP: 通过突变表型推断
18619870 MGI
involved in negative regulation of interleukin-2 production IMP
IMP: 通过突变表型推断
18619870 MGI
involved in negative regulation of pre-B cell receptor expression IMP
IMP: 通过突变表型推断
22949502 MGI
involved in negative regulation of type II interferon production IMP
IMP: 通过突变表型推断
18619870 MGI
involved in positive regulation of MAPK cascade IMP
IMP: 通过突变表型推断
22733818 MGI
involved in positive regulation of cytokine production involved in immune response IMP
IMP: 通过突变表型推断
22733818 MGI
involved in positive regulation of interleukin-12 production IMP
IMP: 通过突变表型推断
22733818 MGI
involved in positive regulation of interleukin-6 production IMP
IMP: 通过突变表型推断
22733818 MGI
involved in positive regulation of macrophage cytokine production IMP
IMP: 通过突变表型推断
22733818 MGI
involved in positive regulation of non-canonical NF-kappaB signal transduction IMP
IMP: 通过突变表型推断
22733818 MGI
involved in positive regulation of protein ubiquitination IMP
IMP: 通过突变表型推断
22733818 MGI
involved in positive regulation of proteolysis involved in protein catabolic process IMP
IMP: 通过突变表型推断
22949502 MGI
involved in positive regulation of receptor catabolic process IMP
IMP: 通过突变表型推断
20519653 MGI
involved in positive regulation of tumor necrosis factor-mediated signaling pathway IMP
IMP: 通过突变表型推断
22733818 MGI
involved in positive regulation of ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
24638062 MGI
involved in positive regulation of ubiquitin-dependent protein catabolic process IMP
IMP: 通过突变表型推断
18619870 MGI
involved in protein localization to lysosome IMP
IMP: 通过突变表型推断
22949502 MGI
involved in protein targeting to lysosome IDA
IDA: 通过直接分析推断
18619870 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in lysosome IDA
IDA: 通过直接分析推断
18619870 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

lysosomal-associated transmembrane protein 5

lysosomal-associated multitransmembrane protein 5

retinoic acid-inducible E3 protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Laptm5 NCBI NCBI:7805