1. Gene
  2. Lbp - lipopolysaccharide binding protein Gene

Lbp - lipopolysaccharide binding protein Gene

种属: Mus musculus

同用名: Ly88; Bpifd2

基因 ID: 16803 | 基因类型: protein coding

关于 Lbp

功能概要

Enables lipopolysaccharide binding activity and signaling receptor binding activity. Involved in several processes, including positive regulation of respiratory burst involved in inflammatory response; positive regulation of tumor necrosis factor production; and response to bacterium. Acts upstream of or within several processes, including defense response to Gram-negative bacterium; leukocyte chemotaxis involved in inflammatory response; and positive regulation of neutrophil chemotaxis. Located in cell surface and extracellular space. Is expressed in brain; heart ventricle; liver lobe; and reproductive system. Orthologous to human LBP (lipopolysaccharide binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Lbp 基因产物(1)

mRNA Protein Name
NM_008489.2 NP_032515.2 lipopolysaccharide-binding protein precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables lipopolysaccharide binding IDA
IDA: 通过直接分析推断
11079463 MGI
enables signaling receptor binding IDA
IDA: 通过直接分析推断
9338787 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acute-phase response IMP
IMP: 通过突变表型推断
12932360 MGI
involved in cellular response to lipopolysaccharide IMP
IMP: 通过突变表型推断
24380872 MGI
acts upstream of or within defense response to Gram-negative bacterium IMP
IMP: 通过突变表型推断
12055258 MGI
involved in defense response to Gram-negative bacterium IMP
IMP: 通过突变表型推断
9338787 MGI
involved in defense response to Gram-positive bacterium IMP
IMP: 通过突变表型推断
12932360 MGI
involved in innate immune response IMP
IMP: 通过突变表型推断
12932360 MGI
acts upstream of or within leukocyte chemotaxis involved in inflammatory response IMP
IMP: 通过突变表型推断
12055258 MGI
involved in macrophage activation involved in immune response IDA
IDA: 通过直接分析推断
12932360 MGI
acts upstream of neutrophil chemotaxis IMP
IMP: 通过突变表型推断
12055258 MGI
acts upstream of or within positive regulation of chemokine production IMP
IMP: 通过突变表型推断
12055258 MGI
acts upstream of or within positive regulation of neutrophil chemotaxis IMP
IMP: 通过突变表型推断
12055258 MGI
involved in positive regulation of respiratory burst involved in inflammatory response IMP
IMP: 通过突变表型推断
9338787 MGI
involved in positive regulation of tumor necrosis factor production IDA
IDA: 通过直接分析推断
12932360 MGI
acts upstream of or within positive regulation of tumor necrosis factor production IMP
IMP: 通过突变表型推断
12055258 MGI
involved in positive regulation of tumor necrosis factor production IMP
IMP: 通过突变表型推断
9338787 MGI
acts upstream of or within response to lipopolysaccharide IMP
IMP: 通过突变表型推断
12055258 MGI
involved in response to lipopolysaccharide IMP
IMP: 通过突变表型推断
9338787 MGI
acts upstream of tumor necrosis factor production IMP
IMP: 通过突变表型推断
12055258 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
12932360 MGI
located in extracellular space IDA
IDA: 通过直接分析推断
9338787 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

lipopolysaccharide-binding protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lbp NCBI NCBI:3929
Macaca fascicularis Lbp NCBI NCBI:102124806
Rattus norvegicus Lbp NCBI NCBI:29469
Macaca mulatta Lbp NCBI NCBI:706109