2. Gene
  3. Lfng - LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase Gene

Lfng - LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 16848 | 基因类型: protein coding

关于 Lfng

功能概要

Enables O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity. Involved in lymphocyte differentiation; negative regulation of Notch signaling pathway involved in somitogenesis; and somitogenesis. Acts upstream of or within several processes, including compartment pattern specification; positive regulation of Notch signaling pathway; and regulation of somitogenesis. Predicted to be located in Golgi membrane. Is expressed in several structures, including alimentary system; embryo ectoderm; genitourinary system; inner ear; and paraxial mesenchyme. Human ortholog(s) of this gene implicated in spondylocostal dysostosis. Orthologous to human LFNG (LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Lfng 基因产物(1)

mRNA Protein Name
NM_008494.3 NP_032520.1 beta-1,3-N-acetylglucosaminyltransferase lunatic fringe precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity IDA
IDA: 通过直接分析推断
16221665 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in T cell differentiation IMP
IMP: 通过突变表型推断
19217325 MGI
acts upstream of or within compartment pattern specification IMP
IMP: 通过突变表型推断
12001066 MGI
involved in marginal zone B cell differentiation IMP
IMP: 通过突变表型推断
19217325 MGI
involved in negative regulation of Notch signaling pathway involved in somitogenesis IMP
IMP: 通过突变表型推断
23072809 MGI
acts upstream of or within ovarian follicle development IMP
IMP: 通过突变表型推断
15659488 MGI
acts upstream of or within positive regulation of Notch signaling pathway IDA
IDA: 通过直接分析推断
15574878 MGI
acts upstream of or within positive regulation of meiotic cell cycle IMP
IMP: 通过突变表型推断
15659488 MGI
acts upstream of or within positive regulation of protein binding IDA
IDA: 通过直接分析推断
15574878 MGI
involved in regulation of Notch signaling pathway IDA
IDA: 通过直接分析推断
16385447 MGI
involved in regulation of Notch signaling pathway IMP
IMP: 通过突变表型推断
28089369 MGI
acts upstream of or within regulation of somitogenesis IMP
IMP: 通过突变表型推断
19779553 MGI
acts upstream of or within somitogenesis IMP
IMP: 通过突变表型推断
18234727 MGI
involved in somitogenesis IMP
IMP: 通过突变表型推断
23072809 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

beta-1,3-N-acetylglucosaminyltransferase lunatic fringe

O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

lunatic fringe

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07601 LFNG Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22217 Lfng Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28739 Lfng Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lfng NCBI NCBI:3955
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