2. Gene
  3. Lipe - lipase, hormone sensitive Gene

Lipe - lipase, hormone sensitive Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: HSL; REH; 4933403G17Rik

基因 ID: 16890 | 基因类型: protein coding

关于 Lipe

功能概要

Enables carboxylic ester hydrolase activity; protein kinase binding activity; and serine hydrolase activity. Involved in ether lipid metabolic process and lipid catabolic process. Acts upstream of or within cellular lipid catabolic process and cellular response to cold. Located in cytosol; lipid droplet; and membrane. Is expressed in adipose tissue; ileum; and male reproductive gland or organ. Human ortholog(s) of this gene implicated in arteriosclerosis; familial partial lipodystrophy type 6; and hypertension. Orthologous to human LIPE (Lipase E, hormone sensitive type). [provided by Alliance of Genome Resources, Apr 2022]

Lipe 基因产物(2)

mRNA Protein Name
NM_001039507.2 NP_001034596.1 hormone-sensitive lipase isoform 2
NM_010719.5 NP_034849.2 hormone-sensitive lipase isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables diacylglycerol lipase activity IDA
IDA: 通过直接分析推断
23066022 MGI
enables monoacylglycerol lipase activity IDA
IDA: 通过直接分析推断
21454566 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
19717842 MGI
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
15878856 MGI
enables retinyl-palmitate esterase activity IDA
IDA: 通过直接分析推断
15550674 MGI
enables serine hydrolase activity IDA
IDA: 通过直接分析推断
16818490 MGI
enables sterol ester esterase activity IDA
IDA: 通过直接分析推断
15550674 MGI
enables triacylglycerol lipase activity IDA
IDA: 通过直接分析推断
15550674 MGI
enables triacylglycerol lipase activity IMP
IMP: 通过突变表型推断
17074755 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to cold IDA
IDA: 通过直接分析推断
30862682 MGI
acts upstream of or within diacylglycerol catabolic process IDA
IDA: 通过直接分析推断
16804080 MGI
involved in diacylglycerol catabolic process IDA
IDA: 通过直接分析推断
23066022 MGI
acts upstream of or within diacylglycerol catabolic process IMP
IMP: 通过突变表型推断
11717312 MGI
involved in ether lipid metabolic process IDA
IDA: 通过直接分析推断
20625037 MGI
involved in lipid catabolic process IDA
IDA: 通过直接分析推断
15878856 MGI
acts upstream of or within long-chain fatty acid catabolic process IDA
IDA: 通过直接分析推断
16804080 MGI
acts upstream of or within triglyceride catabolic process IDA
IDA: 通过直接分析推断
16804080 MGI
acts upstream of or within triglyceride catabolic process IMP
IMP: 通过突变表型推断
11717312 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
15550674 MGI
located in lipid droplet IDA
IDA: 通过直接分析推断
15878856 MGI
located in membrane IDA
IDA: 通过直接分析推断
15550674 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

hormone-sensitive lipase

monoacylglycerol lipase LIPE

retinyl ester hydrolase

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-112083 BAY-3827 Inhibitor 99.66% 否
HY-144734 Pantothenate kinase-IN-1 Inhibitor / 否
HY-RS07687 LIPE Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18621 Lipe Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25107 Lipe Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lipe NCBI NCBI:3991
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