2. Gene
  3. Lmo2 - LIM domain only 2 Gene

Lmo2 - LIM domain only 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ttg2; Rbtn2; Rbtn-2; Rhom-2

基因 ID: 16909 | 基因类型: protein coding

关于 Lmo2

功能概要

Enables chromatin binding activity. Contributes to DNA binding activity. Involved in negative regulation of erythrocyte differentiation. Acts upstream of or within embryonic hemopoiesis and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of protein-containing complex. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Used to study acute lymphoblastic leukemia. Orthologous to human LMO2 (LIM domain only 2). [provided by Alliance of Genome Resources, Apr 2022]

Lmo2 基因产物(4)

mRNA Protein Name
NM_001142335.1 NP_001135807.1 rhombotin-2 isoform 2
NM_001142336.1 NP_001135808.1 rhombotin-2 isoform 3
NM_001142337.1 NP_001135809.1 rhombotin-2 isoform 3
NM_008505.4 NP_032531.2 rhombotin-2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
contributes to DNA binding IDA
IDA: 通过直接分析推断
9391090 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
18184866 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
7568177 MGI
enables transcription factor binding IPI
IPI: 通过物理相互作用推断
9860983 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within embryonic hemopoiesis IGI
IGI: 通过遗传相互作用推断
10631184 MGI
involved in negative regulation of erythrocyte differentiation IMP
IMP: 通过突变表型推断
9391090 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
18184866 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
9391090 MGI
part of protein-containing complex IPI
IPI: 通过物理相互作用推断
9391090 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

rhombotin-2

LIM domain only protein 2

LIM only 2

LMO-2

T-cell translocation protein 2

cysteine-rich protein TTG-2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07718 LMO2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21367 Lmo2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27886 Lmo2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lmo2 NCBI NCBI:4005
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