2. Gene
  3. Lmo4 - LIM domain only 4 Gene

Lmo4 - LIM domain only 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Crp3; Etohi4; A730077C12Rik

基因 ID: 16911 | 基因类型: protein coding

关于 Lmo4

功能概要

Predicted to enable metal ion binding activity. Involved in positive regulation of kinase activity and regulation of cell migration. Acts upstream of or within several processes, including cell differentiation in spinal cord; neural tube closure; and thymus development. Located in cell leading edge and nucleus. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including branchial arch; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Used to study anencephaly. Orthologous to human LMO4 (LIM domain only 4). [provided by Alliance of Genome Resources, Apr 2022]

Lmo4 基因产物(3)

mRNA Protein Name
NM_001161769.1 NP_001155241.1 LIM domain transcription factor LMO4
NM_001161770.1 NP_001155242.1 LIM domain transcription factor LMO4
NM_010723.3 NP_034853.1 LIM domain transcription factor LMO4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
16949565 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9860983 MGI
enables transcription corepressor activity IDA
IDA: 通过直接分析推断
18539116 MGI
enables transcription factor binding IPI
IPI: 通过物理相互作用推断
9860983 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in motor neuron axon guidance IGI
IGI: 通过遗传相互作用推断
18539116 MGI
acts upstream of or within negative regulation of protein-containing complex assembly IDA
IDA: 通过直接分析推断
19666821 MGI
involved in negative regulation of protein-containing complex assembly IDA
IDA: 通过直接分析推断
18539116 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
18539116 MGI
acts upstream of or within neural tube closure IMP
IMP: 通过突变表型推断
14966285 MGI
involved in neural tube closure IMP
IMP: 通过突变表型推断
16949565 MGI
involved in positive regulation of kinase activity IDA
IDA: 通过直接分析推断
25882817 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
17991461 MGI
acts upstream of or within regulation of cell activation IMP
IMP: 通过突变表型推断
19323994 MGI
acts upstream of or within regulation of cell fate specification IMP
IMP: 通过突变表型推断
19323994 MGI
involved in regulation of cell migration IDA
IDA: 通过直接分析推断
25882817 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
9860983 MGI
acts upstream of or within spinal cord association neuron differentiation IGI
IGI: 通过遗传相互作用推断
19323994 MGI
involved in spinal cord motor neuron cell fate specification IMP
IMP: 通过突变表型推断
18539116 MGI
acts upstream of or within spinal cord motor neuron differentiation IDA
IDA: 通过直接分析推断
19666821 MGI
acts upstream of or within thymus development IGI
IGI: 通过遗传相互作用推断
20549734 MGI
acts upstream of or within ventral spinal cord interneuron differentiation IDA
IDA: 通过直接分析推断
19666821 MGI
acts upstream of or within ventricular septum development IMP
IMP: 通过突变表型推断
20549734 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of RNA polymerase II transcription regulator complex IDA
IDA: 通过直接分析推断
9860983 MGI
located in cell leading edge IDA
IDA: 通过直接分析推断
25882817 MGI
located in nucleus IDA
IDA: 通过直接分析推断
9860983 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

LIM domain transcription factor LMO4

LIM domain only protein 4

LMO-4

breast tumor autoantigen

ethanol induced 4

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03260 CSRP3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07720 LMO4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20768 Lmo4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27282 Lmo4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lmo4 NCBI NCBI:8543
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