1. Gene
  2. Loxl3 - lysyl oxidase-like 3 Gene

Loxl3 - lysyl oxidase-like 3 Gene

种属: Mus musculus

同用名: Lor2; Loxl2

基因 ID: 16950 | 基因类型: protein coding

关于 Loxl3

功能概要

Enables fibronectin binding activity and protein-lysine 6-oxidase activity. Involved in several processes, including fibronectin fibril organization; negative regulation of T-helper 17 cell lineage commitment; and peptidyl-lysine oxidation. Located in extracellular space. Is expressed in several structures, including alimentary system; connective tissue; limb mesenchyme; sensory organ; and skeleton. Orthologous to human LOXL3 (Lysyl Oxidase like 3). [provided by Alliance of Genome Resources, Apr 2022]

Loxl3 基因产物(1)

mRNA Protein Name
NM_013586.5 NP_038614.2 lysyl oxidase homolog 3 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables fibronectin binding IDA
IDA: 通过直接分析推断
26954549 MGI
enables protein-lysine 6-oxidase activity IDA
IDA: 通过直接分析推断
26954549 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in fibronectin fibril organization IMP
IMP: 通过突变表型推断
26954549 MGI
involved in inflammatory response IMP
IMP: 通过突变表型推断
28065600 MGI
involved in lung development IMP
IMP: 通过突变表型推断
27645581 MGI
involved in negative regulation of T-helper 17 cell lineage commitment IMP
IMP: 通过突变表型推断
28065600 MGI
involved in peptidyl-lysine oxidation IDA
IDA: 通过直接分析推断
26954549 MGI
involved in positive regulation of integrin-mediated signaling pathway IMP
IMP: 通过突变表型推断
26954549 MGI
involved in roof of mouth development IMP
IMP: 通过突变表型推断
26307084 MGI
involved in somite development IMP
IMP: 通过突变表型推断
26954549 MGI
involved in spinal cord development IMP
IMP: 通过突变表型推断
26307084 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
26954549 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

lysyl oxidase homolog 3

lysyl oxidase-like 2

lysyl oxidase-like protein 3

lysyl oxidase-related protein 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Loxl3 NCBI NCBI:84695