2. Gene
  3. Pfkfb3 - 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Gene

Pfkfb3 - 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: iPFK-2; uPFK-2; E330010H22Rik

基因 ID: 170768 | 基因类型: protein coding

关于 Pfkfb3

功能概要

Predicted to enable 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in fructose 2,6-bisphosphate metabolic process. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; integumental system; nervous system; sensory organ; and skeleton. Used to study extrinsic cardiomyopathy. Orthologous to human PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3). [provided by Alliance of Genome Resources, Apr 2022]

Pfkfb3 基因产物(8)

mRNA Protein Name
NM_001177752.1 NP_001171223.1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform 1
NM_001177753.1 NP_001171224.1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform 2
NM_001177754.1 NP_001171225.1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform 3
NM_001177755.1 NP_001171226.1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform 4
NM_001177756.1 NP_001171227.1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform 5
NM_001177757.1 NP_001171228.1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform 7
NM_001177758.1 NP_001171229.1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform 8
NM_133232.3 NP_573495.2 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform 6
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within apoptotic process IMP
IMP: 通过突变表型推断
35087090 MGI
acts upstream of or within glial cell differentiation IMP
IMP: 通过突变表型推断
35087090 MGI
acts upstream of or within glycolytic process IMP
IMP: 通过突变表型推断
35087090 MGI
acts upstream of or within motor behavior IMP
IMP: 通过突变表型推断
35087090 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3

inducible 6-phosphofructo-2-kinase

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-12203 PFK-158 Inducer 98.88% Phase 1
Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-19824 3PO Inhibitor 99.85% 否
HY-12204 PFK-015 Inhibitor 99.80% 否
HY-123981 5MPN 99.89% 否
HY-101972 AZ-PFKFB3-67 Inhibitor 97.03% 否
HY-101971 AZ PFKFB3 26 Inhibitor 99.23% 否
HY-112808 KAN0438757 Inhibitor 99.41% 否
HY-110156 YZ9 Inhibitor 98.56% 否
HY-153077 PFKFB3-IN-2 Inhibitor 99.86% 否
HY-101972A AZ-PFKFB3-67 quarterhydrate Inhibitor ≥99.0% 否
HY-RS10363 PFKFB3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-110169 (E/Z)-3PO Inhibitor 99.86% 否
HY-RS16558 Pfkfb3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22990 Pfkfb3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pfkfb3 NCBI NCBI:5209
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