2. Gene
  3. Abcc4 - ATP binding cassette subfamily C member 4 Gene

Abcc4 - ATP binding cassette subfamily C member 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Mrp4; RGD1565953

基因 ID: 170924 | 基因类型: protein coding

关于 Abcc4

功能概要

Predicted to enable several functions, including ABC-type transporter activity; glutathione transmembrane transporter activity; and prostaglandin transmembrane transporter activity. Involved in several processes, including bile acid signaling pathway; positive regulation of smooth muscle cell proliferation; and response to xenobiotic stimulus. Located in basolateral plasma membrane and external side of apical plasma membrane. Biomarker of cholestasis and extrahepatic cholestasis. Orthologous to human ABCC4 (ATP binding cassette subfamily C member 4). [provided by Alliance of Genome Resources, Apr 2022]

Abcc4 基因产物(1)

mRNA Protein Name
NM_133411.1 NP_596902.1 ATP-binding cassette subfamily C member 4
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of smooth muscle cell proliferation IMP
IMP: 通过突变表型推断
18636120 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
15047146 RGD
involved in response to tetrachloromethane IEP
IEP: 通过表达模式推断
17544377 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
15047146 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
18619525 RGD
located in external side of apical plasma membrane IDA
IDA: 通过直接分析推断
18619525 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ATP-binding cassette subfamily C member 4

multidrug resistance-associated protein 4

ABC-tranporter

ATP-binding cassette protein C4

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

ATP-binding cassette, subfamily C (CFTR/MRP), member 4

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-19989A MK-571 sodium 99.75% 否
HY-129764 Prostaglandin F3α Substrate / 否
HY-RS00063 ABCC4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20355 Abcc4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26864 Abcc4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Abcc4 NCBI NCBI:10257
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