2. Gene
  3. Gper1 - G protein-coupled estrogen receptor 1 Gene

Gper1 - G protein-coupled estrogen receptor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Gper; GPR41; Gpr30

基因 ID: 171104 | 基因类型: protein coding

关于 Gper1

功能概要

Enables estradiol binding activity and Estrogen receptor activity. Involved in several processes, including apoptotic nuclear changes; cellular response to organic cyclic compound; and positive regulation of signal transduction. Acts upstream of with a positive effect on vasodilation. Located in several cellular components, including dendrite; postsynaptic density; and presynaptic membrane. Orthologous to human GPER1 (G protein-coupled Estrogen receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Gper1 基因产物(1)

mRNA Protein Name
NM_133573.2 NP_598257.2 G-protein coupled estrogen receptor 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled estrogen receptor activity IDA
IDA: 通过直接分析推断
23283935 RGD
enables estradiol binding IMP
IMP: 通过突变表型推断
24262995 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in apoptotic chromosome condensation IDA
IDA: 通过直接分析推断
23907461 RGD
involved in cellular response to estradiol stimulus IDA
IDA: 通过直接分析推断
23283935 RGD
involved in cellular response to mineralocorticoid stimulus IDA
IDA: 通过直接分析推断
23283935 RGD
involved in estrogen receptor signaling pathway IMP
IMP: 通过突变表型推断
20445128 RGD
involved in negative regulation of cell population proliferation IDA
IDA: 通过直接分析推断
23907461 RGD
involved in negative regulation of gene expression IDA
IDA: 通过直接分析推断
23907461 RGD
involved in nuclear fragmentation involved in apoptotic nuclear change IDA
IDA: 通过直接分析推断
23907461 RGD
involved in nuclear receptor-mediated steroid hormone signaling pathway IDA
IDA: 通过直接分析推断
20445128 RGD
involved in positive regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
19717735 RGD
involved in positive regulation of ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
19717735 RGD
involved in positive regulation of apoptotic process IDA
IDA: 通过直接分析推断
23907461 RGD
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
22975889 RGD
involved in positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IDA
IDA: 通过直接分析推断
23907461 RGD
involved in positive regulation of endothelial cell apoptotic process IDA
IDA: 通过直接分析推断
23283935 RGD
involved in positive regulation of epidermal growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
20445128 RGD
involved in positive regulation of extrinsic apoptotic signaling pathway IDA
IDA: 通过直接分析推断
23907461 RGD
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
23907461 RGD
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
23641788 RGD
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: 通过直接分析推断
19717735 RGD
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: 通过突变表型推断
19717735 RGD
involved in positive regulation of protein import into nucleus IMP
IMP: 通过突变表型推断
24262995 RGD
involved in positive regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
20445128 RGD
involved in positive regulation of release of cytochrome c from mitochondria IDA
IDA: 通过直接分析推断
23907461 RGD
involved in positive regulation of voltage-gated sodium channel activity IMP
IMP: 通过突变表型推断
24097558 RGD
involved in serotonin receptor signaling pathway IMP
IMP: 通过突变表型推断
19095043 RGD
acts upstream of positive effect vasodilation IDA
IDA: 通过直接分析推断
23283935 RGD
involved in vasodilation IMP
IMP: 通过突变表型推断
30354811 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
22919059 RGD
located in axon IDA
IDA: 通过直接分析推断
22919059 RGD
located in axon terminus IDA
IDA: 通过直接分析推断
22919059 RGD
located in cytoplasm IDA
IDA: 通过直接分析推断
22919059 RGD
located in dendrite IDA
IDA: 通过直接分析推断
22919059 RGD
located in dendritic shaft IDA
IDA: 通过直接分析推断
22919059 RGD
located in dendritic spine head IDA
IDA: 通过直接分析推断
22919059 RGD
located in dendritic spine membrane IDA
IDA: 通过直接分析推断
22919059 RGD
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
24262995 RGD
located in mitochondrial membrane IDA
IDA: 通过直接分析推断
22919059 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
19095043 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
22919059 RGD
located in postsynaptic density IDA
IDA: 通过直接分析推断
22919059 RGD
located in presynaptic active zone IDA
IDA: 通过直接分析推断
23822769 RGD
located in presynaptic membrane IDA
IDA: 通过直接分析推断
23822769 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

G-protein coupled estrogen receptor 1

G-protein coupled receptor 30

G-protein coupled receptor 41

chemoattractant receptor-like 2

chemokine receptor-like 2

mER

membrane estrogen receptor

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05636 GPER1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18518 Gper1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25000 Gper1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gper1 NCBI NCBI:2852
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