1. Gene
  2. Havcr1 - hepatitis A virus cellular receptor 1 Gene

Havcr1 - hepatitis A virus cellular receptor 1 Gene

种属: Mus musculus

同用名: Tim1; KIM-1; TIM-1; Timd1

基因 ID: 171283 | 基因类型: protein coding

关于 Havcr1

功能概要

Enables phosphatidylserine binding activity. Acts upstream of or within positive regulation of mast cell activation; response to lipopolysaccharide; and response to wounding. Located in brush border and cell surface. Is expressed in brain; dorsal aorta; liver; lung; and reproductive system. Human ortholog(s) of this gene implicated in atopic dermatitis. Orthologous to human HAVCR1 (hepatitis A virus cellular receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Havcr1 基因产物(3)

mRNA Protein Name
NM_001166631.1 NP_001160103.1 hepatitis A virus cellular receptor 1 homolog isoform b precursor
NM_001166632.1 NP_001160104.1 hepatitis A virus cellular receptor 1 homolog isoform b precursor
NM_134248.2 NP_599009.2 hepatitis A virus cellular receptor 1 homolog isoform a precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables phosphatidylserine binding IDA
IDA: 通过直接分析推断
18083575 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15793576 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within positive regulation of mast cell activation IDA
IDA: 通过直接分析推断
20566714 MGI
acts upstream of or within response to lipopolysaccharide IDA
IDA: 通过直接分析推断
29402223 MGI
acts upstream of or within response to wounding IMP
IMP: 通过突变表型推断
29402223 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in brush border IDA
IDA: 通过直接分析推断
29402223 MGI
located in cell surface IDA
IDA: 通过直接分析推断
18083575 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

hepatitis A virus cellular receptor 1 homolog

HAVcr-1

T-cell immunoglobulin and mucin domain containing 1

T-cell immunoglobulin mucin receptor 1

TIMD-1

kidney injury molecule 1

t cell immunoglobulin and mucin domain-containing protein 1

t cell membrane protein 1

Havcr1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Havcr1 Q5QNS5 Timd4 Mus musculus Q6U7R4 15793576
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 Havcr1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71365 TIM-1/KIM-1/HAVCR Protein, Mouse (HEK293, C-His) Q5QNS5-1 (Y22-T212) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Havcr1 NCBI NCBI:26762
Canis familiaris Havcr1 NCBI NCBI:612069
Macaca fascicularis Havcr1 NCBI NCBI:102141332
Rattus norvegicus Havcr1 NCBI NCBI:286934