1. Gene
  2. NLRP6 - Nlrp6 NLR family, pyrin domain containing 6 Gene

NLRP6 - Nlrp6 NLR family, pyrin domain containing 6 Gene

种属: Rattus norvegicus

同用名: Avr; Navr; Nalp6; Non-AVR; Navr/Avr

基因 ID: 171390 | 基因类型: protein coding

关于 NLRP6

功能概要

The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. [provided by RefSeq, Feb 2013]

NLRP6 基因产物(1)

mRNA Protein Name
NM_134375.5 NP_599202.4 NACHT, LRR and PYD domains-containing protein 6
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables peptide binding IMP
IMP: 通过突变表型推断
7489366 RGD
enables vasopressin receptor activity IDA
IDA: 通过直接分析推断
18413781 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

NACHT, LRR and PYD domains-containing protein 6

NACHT, LRR and PYD domains-containing protein 6-like

NACHT, leucine rich repeat and PYD containing 6

angiotensin II/vasopressin receptor

dual angiotensin II/vasopressin receptor

non-angiotensin-vasopressin receptor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens NLRP6 NCBI NCBI:171389