2. Gene
  3. Mapkapk5 - MAP kinase-activated protein kinase 5 Gene

Mapkapk5 - MAP kinase-activated protein kinase 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: MK5; PRAK

基因 ID: 17165 | 基因类型: protein coding

关于 Mapkapk5

功能概要

Enables mitogen-activated protein kinase binding activity; p53 binding activity; and protein serine/threonine kinase activity. Involved in Ras protein signal transduction; negative regulation of TOR signaling; and stress-induced premature senescence. Acts upstream of or within positive regulation of dendritic spine development. Located in cytoplasm; nucleus; and septin Cytoskeleton. Part of protein-containing complex. Is expressed in brain; embryo; and lung. Orthologous to human MAPKAPK5 (MAPK activated protein kinase 5). [provided by Alliance of Genome Resources, Apr 2022]

Mapkapk5 基因产物(1)

mRNA Protein Name
NM_010765.2 NP_034895.1 MAP kinase-activated protein kinase 5
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mitogen-activated protein kinase binding IPI
IPI: 通过物理相互作用推断
15577943 MGI
enables p53 binding IDA
IDA: 通过直接分析推断
17254968 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15538386 MGI
enables protein kinase activity IDA
IDA: 通过直接分析推断
15538386 MGI
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
15577943 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Ras protein signal transduction IMP
IMP: 通过突变表型推断
17254968 MGI
involved in negative regulation of TOR signaling IDA
IDA: 通过直接分析推断
21336308 MGI
acts upstream of or within positive regulation of dendritic spine development IGI
IGI: 通过遗传相互作用推断
22508986 MGI
acts upstream of or within positive regulation of dendritic spine development IMP
IMP: 通过突变表型推断
22508986 MGI
involved in stress-induced premature senescence IMP
IMP: 通过突变表型推断
17254968 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15538386 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15538386 MGI
part of protein-containing complex IDA
IDA: 通过直接分析推断
22508986 MGI
located in septin cytoskeleton IDA
IDA: 通过直接分析推断
22508986 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

MAP kinase-activated protein kinase 5

MAPK-activated protein kinase 5

MAPKAP kinase 5

MAPKAPK-5

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-136848 SM1-71 Inhibitor 96.09% 否
HY-148062 RSS0680 99.85% 否
HY-RS08135 MAPKAPK5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17135 Mapkapk5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23581 Mapkapk5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mapkapk5 NCBI NCBI:8550
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