1. Gene
  2. Mark3 - MAP/microtubule affinity regulating kinase 3 Gene

Mark3 - MAP/microtubule affinity regulating kinase 3 Gene

种属: Mus musculus

同用名: ETK1; Emk2; ETK-1; MPK10; C-TAK1; 1600015G02Rik; A430080F22Rik

基因 ID: 17169 | 基因类型: protein coding

关于 Mark3

功能概要

Predicted to enable protein serine/threonine kinase activity and tau-protein kinase activity. Predicted to be involved in several processes, including negative regulation of hippo signaling; peptidyl-serine autophosphorylation; and positive regulation of protein binding activity. Predicted to act upstream of or within phosphorylation. Predicted to be located in dendrite. Predicted to be active in cytoplasm and plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; liver; retina; and spleen. Human ortholog(s) of this gene implicated in visual impairment and progressive phthisis bulbi. Orthologous to human MARK3 (microtubule affinity regulating kinase 3). [provided by Alliance of Genome Resources, Apr 2022]

Mark3 基因产物(4)

mRNA Protein Name
NM_001370744.1 NP_001357673.1 MAP/microtubule affinity-regulating kinase 3 isoform 3
NM_001370745.1 NP_001357674.1 MAP/microtubule affinity-regulating kinase 3 isoform 4
NM_021516.4 NP_067491.2 MAP/microtubule affinity-regulating kinase 3 isoform 1
NM_022801.4 NP_073712.2 MAP/microtubule affinity-regulating kinase 3 isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
28087714 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

MAP/microtubule affinity-regulating kinase 3

ELKL motif kinase 2

EMK-2

EMK2/MARK3 serine-threonine protein kinase

MPK-10

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mark3 NCBI NCBI:4140