1. Gene
  2. Mc5r - melanocortin 5 receptor Gene

Mc5r - melanocortin 5 receptor Gene

中文名称:黑皮质素 5 受体

种属: Mus musculus

基因 ID: 17203 | 基因类型: protein coding

关于 Mc5r

Chromosome 18: 68,470,575-68,475,517 forward strand.GRCm39:CM001011.3

This gene has 1 transcript (splice variant), 183 orthologues, 18 paralogues and is associated with 6 phenotypes. Broad expression in bladder adult (RPKM 1.6), mammary gland adult (RPKM 1.2) and 17 other tissues.

功能概要

预测该基因编码的蛋白编码的蛋白可启动激素结合活性和黑皮质素受体活性。预计参与腺苷酸环化酶激活 G 蛋白偶联受体信号通路和代谢过程的调控。预测作用于信号转导的上游或内部。预测位于膜中。预计是膜的组成部分。预计在细胞质和质膜中有活性。在皮肤中表达。与人类 MC5R(黑皮质素 5 受体)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable hormone binding activity and Melanocortin Receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in skin. Orthologous to human MC5R (melanocortin 5 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Mc5r 基因产物(1)

mRNA Protein Name
NM_013596.3 NP_038624.3 melanocortin receptor 5

Mc5r 蛋白结构

7tm_GPCRs

7tm_GPCRs: cl28897 (36 - 305)

7tm_GPCRs

7tm_GPCRs: cd14964 (38 - 62)

7tm_GPCRs

7tm_GPCRs: cd14964 (71 - 93)

7tm_GPCRs

7tm_GPCRs: cd14964 (115 - 137)

7tm_GPCRs

7tm_GPCRs: cd14964 (160 - 176)

7tm_GPCRs

7tm_GPCRs: cd14964 (182 - 205)

7tm_GPCRs

7tm_GPCRs: cd14964 (236 - 258)

7tm_GPCRs

7tm_GPCRs: cd14964 (273 - 298)

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  • 325 a.a.
蛋白主名 其他名称

melanocortin receptor 5

MC5-R

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mc5r NCBI NCBI:4161