1. Gene
  2. Rab8a - RAB8A, member RAS oncogene family Gene

Rab8a - RAB8A, member RAS oncogene family Gene

种属: Mus musculus

同用名: Mel

基因 ID: 17274 | 基因类型: protein coding

关于 Rab8a

功能概要

Predicted to enable several functions, including GTPase activity; guanyl ribonucleotide binding activity; and Myosin V binding activity. Predicted to be involved in several processes, including cellular response to Insulin stimulus; plasma membrane bounded cell projection organization; and protein transport. Predicted to act upstream of or within autophagy; cell projection organization; and protein transport. Located in several cellular components, including ciliary basal body; ciliary base; and cytoplasmic vesicle. Is expressed in neural retina and photoreceptor layer. Orthologous to human RAB8A (RAB8A, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab8a 基因产物(1)

mRNA Protein Name
NM_023126.2 NP_075615.2 ras-related protein Rab-8A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11773082 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cilium assembly IMP
IMP: 通过突变表型推断
25860027 MGI
involved in protein localization to cilium IMP
IMP: 通过突变表型推断
25860027 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in ciliary basal body IDA
IDA: 通过直接分析推断
19625297 MGI
located in ciliary base IDA
IDA: 通过直接分析推断
24947469 MGI
located in ciliary membrane IDA
IDA: 通过直接分析推断
29038301 MGI
located in cilium IDA
IDA: 通过直接分析推断
24469809 MGI
located in cilium IMP
IMP: 通过突变表型推断
20048263 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
20592197 MGI
located in non-motile cilium IDA
IDA: 通过直接分析推断
19625297 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
18094055 MGI
located in recycling endosome IDA
IDA: 通过直接分析推断
18094055 MGI
located in trans-Golgi network transport vesicle IDA
IDA: 通过直接分析推断
17765678 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ras-related protein Rab-8A

cell line NK14 derived transforming oncogene

oncogene c-mel

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rab8a NCBI NCBI:4218