1. Gene
  2. Mesp1 - mesoderm posterior 1 Gene

Mesp1 - mesoderm posterior 1 Gene

种属: Mus musculus

同用名: bHLHc5

基因 ID: 17292 | 基因类型: protein coding

关于 Mesp1

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including heart development; regulation of cell fate specification; and regulation of transcription, DNA-templated. Acts upstream of or within several processes, including cardioblast anterior-lateral migration; mesodermal cell migration; and signal transduction involved in regulation of gene expression. Located in nucleus. Is expressed in several structures, including allantois; central nervous system; embryo mesenchyme; primitive streak; and sensory organ. Orthologous to human MESP1 (mesoderm posterior bHLH transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Mesp1 基因产物(1)

mRNA Protein Name
NM_008588.2 NP_032614.2 mesoderm posterior protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cardiac cell fate determination IDA
IDA: 通过直接分析推断
18593560 MGI
involved in cardioblast anterior-lateral migration IMP
IMP: 通过突变表型推断
10393122 MGI
acts upstream of or within cardioblast migration IMP
IMP: 通过突变表型推断
10393122 MGI
involved in cardioblast migration to the midline involved in heart field formation IMP
IMP: 通过突变表型推断
10393122 MGI
involved in embryonic heart tube morphogenesis IMP
IMP: 通过突变表型推断
10393122 MGI
involved in gastrulation IEP
IEP: 通过表达模式推断
8787751 MGI
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
23352431 MGI
involved in growth involved in heart morphogenesis IMP
IMP: 通过突变表型推断
10393122 MGI
involved in heart induction IDA
IDA: 通过直接分析推断
18297060 MGI
involved in heart looping IMP
IMP: 通过突变表型推断
10393122 MGI
acts upstream of or within heart morphogenesis IMP
IMP: 通过突变表型推断
10393122 MGI
involved in lateral mesoderm development IMP
IMP: 通过突变表型推断
10393122 MGI
acts upstream of or within mesodermal cell migration IGI
IGI: 通过遗传相互作用推断
10393122 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
18593560 MGI
involved in negative regulation of canonical Wnt signaling pathway IDA
IDA: 通过直接分析推断
18297060 MGI
involved in negative regulation of endodermal cell fate specification IDA
IDA: 通过直接分析推断
18593560 MGI
involved in negative regulation of mesodermal cell fate specification IDA
IDA: 通过直接分析推断
18593560 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
18593560 MGI
involved in positive regulation of Notch signaling pathway IDA
IDA: 通过直接分析推断
18593560 MGI
involved in positive regulation of hepatocyte differentiation IDA
IDA: 通过直接分析推断
18593560 MGI
involved in positive regulation of striated muscle cell differentiation IDA
IDA: 通过直接分析推断
18593560 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
18297060 MGI
involved in secondary heart field specification IDA
IDA: 通过直接分析推断
18593560 MGI
acts upstream of or within signal transduction involved in regulation of gene expression IDA
IDA: 通过直接分析推断
18462699 MGI
involved in sinus venosus morphogenesis IMP
IMP: 通过突变表型推断
10393122 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
18593560 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

mesoderm posterior protein 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mesp1 NCBI NCBI:55897