1. Gene
  2. Mfng - MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase Gene

Mfng - MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase Gene

种属: Mus musculus

基因 ID: 17305 | 基因类型: protein coding

关于 Mfng

功能概要

Predicted to enable O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity. Involved in marginal zone B cell differentiation and regulation of Notch signaling pathway. Acts upstream of or within blastocyst formation; positive regulation of Notch signaling pathway; and positive regulation of protein binding activity. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of Golgi membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; peripheral nervous system; and sensory organ. Orthologous to human MFNG (MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Mfng 基因产物(2)

mRNA Protein Name
NM_001411378.1 NP_001398307.1 beta-1,3-N-acetylglucosaminyltransferase manic fringe isoform 2
NM_008595.3 NP_032621.1 beta-1,3-N-acetylglucosaminyltransferase manic fringe isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity IDA
IDA: 通过直接分析推断
16221665 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21946561 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within blastocyst formation IMP
IMP: 通过突变表型推断
27869233 MGI
involved in marginal zone B cell differentiation IMP
IMP: 通过突变表型推断
19217325 MGI
acts upstream of or within positive regulation of Notch signaling pathway IDA
IDA: 通过直接分析推断
15574878 MGI
acts upstream of or within positive regulation of protein binding IDA
IDA: 通过直接分析推断
15574878 MGI
involved in regulation of Notch signaling pathway IMP
IMP: 通过突变表型推断
28089369 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

beta-1,3-N-acetylglucosaminyltransferase manic fringe

O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

manic fringe homolog

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mfng NCBI NCBI:4242