2. Gene
  3. Mgat3 - mannoside acetylglucosaminyltransferase 3 Gene

Mgat3 - mannoside acetylglucosaminyltransferase 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: GnT-III; 1110038J12Rik

基因 ID: 17309 | 基因类型: protein coding

关于 Mgat3

功能概要

Enables beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity. Acts upstream of or within several processes, including amyloid-beta metabolic process; negative regulation of lysosomal protein catabolic process; and positive regulation of protein localization to early endosome. Is expressed in several structures, including alimentary system; metanephros; and nervous system. Orthologous to human MGAT3 (beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Mgat3 基因产物(1)

mRNA Protein Name
NM_010795.4 NP_034925.2 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity IMP
IMP: 通过突变表型推断
25592972 MGI
enables glycosyltransferase activity IDA
IDA: 通过直接分析推断
24619415 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within N-acetylglucosamine metabolic process IDA
IDA: 通过直接分析推断
24619415 MGI
acts upstream of or within amyloid-beta metabolic process IMP
IMP: 通过突变表型推断
25592972 MGI
acts upstream of or within cellular response to oxidative stress IMP
IMP: 通过突变表型推断
26467158 MGI
acts upstream of or within cognition IMP
IMP: 通过突变表型推断
25592972 MGI
acts upstream of lysosomal protein catabolic process IMP
IMP: 通过突变表型推断
25592972 MGI
acts upstream of or within negative regulation of lysosomal protein catabolic process IMP
IMP: 通过突变表型推断
25592972 MGI
acts upstream of or within positive regulation of protein localization to early endosome IMP
IMP: 通过突变表型推断
25592972 MGI
acts upstream of or within protein N-linked glycosylation IMP
IMP: 通过突变表型推断
25592972 MGI
acts upstream of protein localization to early endosome IMP
IMP: 通过突变表型推断
25592972 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase

N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III

glcNAc-T III

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-32219 T863 Inhibitor 99.83% 否
HY-108339 PF-06471553 Inhibitor 98.29% 否
HY-146280 mGAT3/4-IN-1 Inhibitor / 否
HY-146281 mGAT3/4-IN-2 Inhibitor / 否
HY-146282 mGAT-IN-1 Inhibitor / 否
HY-RS08403 MGAT3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20988 Mgat3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27505 Mgat3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mgat3 NCBI NCBI:4248
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