2. Gene
  3. Mip - major intrinsic protein of lens fiber Gene

Mip - major intrinsic protein of lens fiber Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Cat; Cts; Hfi; Lop; Svl; Aqp0; MP26; MIP26; shrivelled

基因 ID: 17339 | 基因类型: protein coding

关于 Mip

功能概要

Enables water channel activity. A structural constituent of eye lens. Acts upstream of or within lens development in camera-type eye; visual perception; and water transport. Located in plasma membrane. Is expressed in several structures, including eye; femur; and main olfactory bulb. Used to study cataract 15 multiple types. Human ortholog(s) of this gene implicated in cataract and cataract 15 multiple types. Orthologous to human MIP (major intrinsic protein of lens fiber). [provided by Alliance of Genome Resources, Apr 2022]

Mip 基因产物(1)

mRNA Protein Name
NM_008600.5 NP_032626.2 lens fiber major intrinsic protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18056999 MGI
enables structural constituent of eye lens IDA
IDA: 通过直接分析推断
11773604 MGI
enables water channel activity IMP
IMP: 通过突变表型推断
11773604 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within lens development in camera-type eye IMP
IMP: 通过突变表型推断
7333462 MGI
acts upstream of or within visual perception IMP
IMP: 通过突变表型推断
11773604 MGI
acts upstream of or within water transport IMP
IMP: 通过突变表型推断
11773604 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
17377981 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
9620080 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lens fiber major intrinsic protein

aquaporin-0

cataract and small eye

dominant cataract

hydropic fibers

lens opacity

major intrinsic protein of eye lens fiber

相关产品

Clinical Phase
生物活性分子 (4)
目录号 产品名 作用方式
纯度 Phase
HY-B0498 Bindarit Inhibitor 99.53% Phase 3
HY-B0155 Vicriviroc / Phase 3
HY-19974 TAK-220 99.95% Phase 1
HY-P3627 Nagrestipen / Phase 1
Pre-clinical Phase
生物活性分子 (25)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-139644 MIPS521 Agonist 98.21% 否
HY-156371 MIPS-21335 Inhibitor 99.61% 否
HY-P4191A Met-RANTES (human) (acetate) Antagonist 99.62% 否
HY-149650 TLR4 agonist-1 Agonist / 否
HY-P4191 Met-RANTES (human) Antagonist / 否
HY-W014081 Ethyl 3-coumarincarboxylate 99.81% 否
HY-123661 MIPS1455 / 否
HY-123733 MIP-1095 Inhibitor / 否
HY-123733A MIP-1095 TFA 99.76% 否
HY-129615 MIP-1072 Inhibitor / 否
HY-149650A TLR4 agonist-1 TEA Agonist / 否
HY-149861 Mip-IN-1 Inhibitor / 否
HY-15544 CCR1 antagonist 10 Antagonist / 否
HY-161901 BC-1293 Inhibitor / 否
HY-B0155B Vicriviroc malate / 否
HY-RS08460 MIP Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08461 MIPEP Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS14859 TNPO1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-103360B trans-J-113863 Antagonist / 否
HY-120265 MIPS-9922 Inhibitor / 否
HY-168149 Mip-IN-2 Inhibitor / 否
HY-RS19300 Mip Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20118 Tnpo1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22639 Mipep Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25791 Mip Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mip NCBI NCBI:4284
Rattus norvegicus Mip NCBI NCBI:25480
Macaca mulatta Mip NCBI NCBI:712901
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