2. Gene
  3. Gbp4 - guanylate binding protein 4 Gene

Gbp4 - guanylate binding protein 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Mpa2; Mag-2; Mpa-2

基因 ID: 17472 | 基因类型: protein coding

关于 Gbp4

功能概要

Predicted to enable GTP binding activity and GTPase activity. Acts upstream of or within several processes, including cellular response to interferon-gamma; negative regulation of macromolecule metabolic process; and negative regulation of protein import into nucleus. Predicted to be active in cytoplasmic vesicle. Orthologous to human GBP6 (guanylate binding protein family member 6). [provided by Alliance of Genome Resources, Apr 2022]

Gbp4 基因产物(6)

mRNA Protein Name
NM_001256005.1 NP_001242934.1 macrophage activation 2 isoform 1
NM_001359079.1 NP_001346008.1 macrophage activation 2 isoform 3
NM_001359080.1 NP_001346009.1 macrophage activation 2 isoform 2
NM_001359081.1 NP_001346010.1 macrophage activation 2 isoform 2
NM_001359082.1 NP_001346011.1 macrophage activation 2 isoform 2
NM_008620.4 NP_032646.2 macrophage activation 2 isoform 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
22095711 MGI
enables ubiquitin-protein transferase inhibitor activity IDA
IDA: 通过直接分析推断
22095711 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to type II interferon IDA
IDA: 通过直接分析推断
18025219 MGI
involved in negative regulation of interferon-alpha production IDA
IDA: 通过直接分析推断
22095711 MGI
acts upstream of or within negative regulation of interferon-alpha production IMP
IMP: 通过突变表型推断
22095711 MGI
acts upstream of or within negative regulation of protein import into nucleus IDA
IDA: 通过直接分析推断
22095711 MGI
acts upstream of or within negative regulation of protein phosphorylation IDA
IDA: 通过直接分析推断
22095711 MGI
acts upstream of or within negative regulation of protein ubiquitination IGI
IGI: 通过遗传相互作用推断
22095711 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
22095711 MGI
acts upstream of or within regulation of defense response to virus IMP
IMP: 通过突变表型推断
22095711 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

macrophage activation 2

guanylate nucleotide binding protein 4

guanylate-binding protein 4 homolog

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05310 GBP4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18935 Gbp4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22180 Gbp3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25425 Gbp4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gbp4 NCBI NCBI:115361
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