2. Gene
  3. Clec4d - C-type lectin domain family 4, member d Gene

Clec4d - C-type lectin domain family 4, member d Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: mcl; Mpcl; Clecsf8

基因 ID: 17474 | 基因类型: protein coding

关于 Clec4d

功能概要

Enables immunoglobulin receptor binding activity. Involved in Antifungal innate immune response; positive regulation of I-kappaB kinase/NF-kappaB signaling; and positive regulation of myeloid dendritic cell activation. Acts upstream of or within several processes, including Fc-gamma Receptor signaling pathway; T cell differentiation involved in immune response; and defense response to Other organism. Located in plasma membrane. Is expressed in bone marrow; lung; lymph node; and spleen. Orthologous to human CLEC4D (C-type lectin domain family 4 member D). [provided by Alliance of Genome Resources, Apr 2022]

Clec4d 基因产物(2)

mRNA Protein Name
NM_001163161.1 NP_001156633.1 C-type lectin domain family 4 member D isoform 2
NM_010819.4 NP_034949.3 C-type lectin domain family 4 member D isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables immunoglobulin receptor binding IPI
IPI: 通过物理相互作用推断
23602766 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Fc-gamma receptor signaling pathway IDA
IDA: 通过直接分析推断
23602766 MGI
acts upstream of or within T cell differentiation involved in immune response IMP
IMP: 通过突变表型推断
23602766 MGI
acts upstream of or within adaptive immune response IMP
IMP: 通过突变表型推断
23602766 MGI
involved in antifungal innate immune response IMP
IMP: 通过突变表型推断
23911656 MGI
acts upstream of or within defense response to bacterium IMP
IMP: 通过突变表型推断
23602766 MGI
acts upstream of or within innate immune response IMP
IMP: 通过突变表型推断
23602766 MGI
involved in positive regulation of canonical NF-kappaB signal transduction IMP
IMP: 通过突变表型推断
23911656 MGI
involved in positive regulation of myeloid dendritic cell activation IMP
IMP: 通过突变表型推断
23602766 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
23602766 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

C-type lectin domain family 4 member D

C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 8

C-type lectin, superfamily member 8

DC-associated C-type lectin 3

dectin-3

dendritic cell-associated C-type lectin 3

macrophage C-type lectin

macrophage-restric

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02793 CLEC4D Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19771 Clec4d Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26268 Clec4d Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Clec4d NCBI NCBI:338339
Rattus norvegicus Clec4d NCBI NCBI:362432
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