1. Gene
  2. mt-Nd2 - NADH dehydrogenase 2, mitochondrial Gene

mt-Nd2 - NADH dehydrogenase 2, mitochondrial Gene

种属: Mus musculus (strain: C57BL/6J)

同用名: ND2

基因 ID: 17717 | 基因类型: protein coding

关于 mt-Nd2

功能概要

Predicted to enable NADH dehydrogenase (ubiquinone) activity; ionotropic glutamate receptor binding activity; and protein kinase binding activity. Acts upstream of or within Reactive Oxygen Species metabolic process. Located in mitochondrion. Is expressed in early conceptus and secondary oocyte. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; multiple sclerosis; myocardial infarction; neurodegenerative disease (multiple); and urinary bladder Cancer. Orthologous to human MT-ND2 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

mt-Nd2 基因产物(2)

mRNA Protein Name
NP_904329.1 NADH dehydrogenase subunit 2 (mitochondrion) [Mus musculus]
NP_904329.1 NADH dehydrogenase subunit 2 (mitochondrion) [Mus musculus]
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within reactive oxygen species metabolic process IDA
IDA: 通过直接分析推断
17189252 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

NADH dehydrogenase subunit 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens mt-Nd2 NCBI NCBI:4536