2. Gene
  3. Commd1 - COMM domain containing 1 Gene

Commd1 - COMM domain containing 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Murr1; U2/Mu

基因 ID: 17846 | 基因类型: protein coding

关于 Commd1

功能概要

Predicted to enable several functions, including low-density lipoprotein particle receptor binding activity; phosphatidylinositol-3,4-bisphosphate binding activity; and phospholipid binding activity. Acts upstream of or within several processes, including Cholesterol homeostasis; low-density lipoprotein particle clearance; and positive regulation of protein localization. Located in endosome. Is expressed in several structures, including central nervous system; extraembryonic component; future brain; limb bud; and otocyst. Orthologous to human COMMD1 (copper metabolism domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Commd1 基因产物(2)

mRNA Protein Name
NM_001361661.1 NP_001348590.1 COMM domain-containing protein 1 isoform 2
NM_144514.2 NP_653097.2 COMM domain-containing protein 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17371845 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cholesterol homeostasis IMP
IMP: 通过突变表型推断
26965651 MGI
acts upstream of or within low-density lipoprotein particle clearance IMP
IMP: 通过突变表型推断
26965651 MGI
acts upstream of or within negative regulation of hypoxia-inducible factor-1alpha signaling pathway IMP
IMP: 通过突变表型推断
17371845 MGI
acts upstream of or within positive regulation of cholesterol import IMP
IMP: 通过突变表型推断
26965651 MGI
acts upstream of or within positive regulation of endosome to plasma membrane protein transport IMP
IMP: 通过突变表型推断
26965651 MGI
acts upstream of or within positive regulation of protein localization to cell surface IMP
IMP: 通过突变表型推断
26965651 MGI
acts upstream of or within protein destabilization IMP
IMP: 通过突变表型推断
17371845 MGI
acts upstream of protein localization to cell surface IMP
IMP: 通过突变表型推断
26965651 MGI
acts upstream of or within regulation of plasma lipoprotein particle levels IMP
IMP: 通过突变表型推断
26965651 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endosome IDA
IDA: 通过直接分析推断
26965651 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

COMM domain-containing protein 1

U2af1-rs1 region 1

copper metabolism domain containing 1

protein Murr1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P11115 CIGB-552 / 否
HY-RS03009 COMMD1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21109 Commd1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27628 Commd1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Commd1 NCBI NCBI:150684
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