1. Gene
  2. Mxi1 - MAX interactor 1, dimerization protein Gene

Mxi1 - MAX interactor 1, dimerization protein Gene

种属: Mus musculus

同用名: Mad2; Gm10197; bHLHc11

基因 ID: 17859 | 基因类型: protein coding

关于 Mxi1

功能概要

This gene encodes a protein containing a helix-loop-helix domain characteristic of transcription factors, which allows heterodimerization and sequence-specific DNA binding. The encoded protein is related to a family of Myc/Max/Mad proteins that are involved in the regulation of several cellular processes. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate Myc function. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Mxi1 基因产物(7)

mRNA Protein Name
NM_001008542.3 NP_001008542.2 max-interacting protein 1 isoform b
NM_001008543.3 NP_001008543.1 max-interacting protein 1 isoform c
NM_001360345.1 NP_001347274.1 max-interacting protein 1 isoform c
NM_001360346.1 NP_001347275.1 max-interacting protein 1 isoform c
NM_001360347.1 NP_001347276.1 max-interacting protein 1 isoform c
NM_001360348.1 NP_001347277.1 max-interacting protein 1 isoform d
NM_010847.4 NP_034977.1 max-interacting protein 1 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
8649810 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within blastocyst formation IMP
IMP: 通过突变表型推断
27869233 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15467743 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
15467743 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

max-interacting protein 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mxi1 NCBI NCBI:4601