2. Gene
  3. Nbr1 - NBR1, autophagy cargo receptor Gene

Nbr1 - NBR1, autophagy cargo receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: mKIAA0049

基因 ID: 17966 | 基因类型: protein coding

关于 Nbr1

功能概要

Enables mitogen-activated protein kinase binding activity. Involved in negative regulation of osteoblast differentiation; regulation of bone mineralization; and regulation of stress-activated MAPK cascade. Located in late endosome; mitochondrial intermembrane space; and phagophore assembly site. Colocalizes with autophagosome. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and immune system. Orthologous to human NBR1 (NBR1 Autophagy cargo receptor). [provided by Alliance of Genome Resources, Apr 2022]

Nbr1 基因产物(4)

mRNA Protein Name
NM_001252220.1 NP_001239149.1 next to BRCA1 gene 1 protein isoform 1
NM_001252222.1 NP_001239151.1 next to BRCA1 gene 1 protein isoform 2
NM_001252223.1 NP_001239152.1 next to BRCA1 gene 1 protein isoform 3
NM_008676.3 NP_032702.1 next to BRCA1 gene 1 protein isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mitogen-activated protein kinase binding IDA
IDA: 通过直接分析推断
20616007 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
19250911 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of osteoblast differentiation IMP
IMP: 通过突变表型推断
20616007 MGI
involved in regulation of bone mineralization IMP
IMP: 通过突变表型推断
20616007 MGI
involved in regulation of stress-activated MAPK cascade IMP
IMP: 通过突变表型推断
20616007 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
colocalizes with autophagosome IDA
IDA: 通过直接分析推断
20616007 MGI
located in late endosome IDA
IDA: 通过直接分析推断
19250911 MGI
located in mitochondrial intermembrane space IDA
IDA: 通过直接分析推断
25002142 MGI
located in phagophore assembly site IDA
IDA: 通过直接分析推断
21220506 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

next to BRCA1 gene 1 protein

membrane component chromosome 17 surface marker 2 homolog

neighbor of BRCA1 gene 1 protein

next to the Brca1

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-146130 ATG7-IN-2 Inhibitor 99.32% 否
HY-146131 ATG7-IN-3 Inhibitor 99.26% 否
HY-RS09061 NBR1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17332 Nbr1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23787 Nbr1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nbr1 NCBI NCBI:4077
Macaca fascicularis Nbr1 NCBI NCBI:102118025
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z