2. Gene
  3. Ncf2 - neutrophil cytosolic factor 2 Gene

Ncf2 - neutrophil cytosolic factor 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: NOXA2; Ncf-2; p67phox

基因 ID: 17970 | 基因类型: protein coding

关于 Ncf2

功能概要

Enables small GTPase binding activity. Contributes to superoxide-generating NAD(P)H oxidase activity. Acts upstream of or within superoxide anion generation. Located in acrosomal vesicle. Is expressed in several structures, including hemolymphoid system; limb; and liver. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal recessive chronic granulomatous disease cytochrome b-positive type II; and rheumatoid arthritis. Orthologous to human NCF2 (neutrophil cytosolic factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Ncf2 基因产物(1)

mRNA Protein Name
NM_010877.5 NP_035007.1 neutrophil cytosol factor 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
9490028 MGI
enables small GTPase binding IPI
IPI: 通过物理相互作用推断
9490028 MGI
contributes to superoxide-generating NAD(P)H oxidase activity IDA
IDA: 通过直接分析推断
9490028 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within superoxide anion generation IDA
IDA: 通过直接分析推断
9490028 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in acrosomal vesicle IDA
IDA: 通过直接分析推断
15850784 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
15850784 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neutrophil cytosol factor 2

67 kDa neutrophil oxidase factor

NADPH oxidase activator 2

NADPH oxidase subunit (67kDa)

neutrophil NADPH oxidase factor 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09078 NCF2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19358 Ncf2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25849 Ncf2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ncf2 NCBI NCBI:4688
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