1. Gene
  2. Ninj1 - ninjurin 1 Gene

Ninj1 - ninjurin 1 Gene

种属: Mus musculus

基因 ID: 18081 | 基因类型: protein coding

关于 Ninj1

功能概要

Enables cell-cell adhesion mediator activity and lipopolysaccharide binding activity. Involved in several processes, including leukocyte chemotaxis; pericyte cell migration; and positive regulation of osteoclast development. Acts upstream of or within hyaloid vascular plexus regression and positive regulation of cell-matrix adhesion. Located in extracellular region; filopodium membrane; and synaptic membrane. Is integral component of plasma membrane. Is expressed in several structures, including body cavity or lining; central nervous system; eye; genitourinary system; and vertebral axis musculature. Orthologous to human NINJ1 (ninjurin 1). [provided by Alliance of Genome Resources, Apr 2022]

Ninj1 基因产物(1)

mRNA Protein Name
NM_013610.3 NP_038638.1 ninjurin-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cell adhesion mediator activity IDA
IDA: 通过直接分析推断
24347169 MGI
enables cell-cell adhesion mediator activity IMP
IMP: 通过突变表型推断
25766274 MGI
enables lipopolysaccharide binding IDA
IDA: 通过直接分析推断
26677008 MGI
enables membrane destabilizing activity IDA
IDA: 通过直接分析推断
33472215 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell adhesion IDA
IDA: 通过直接分析推断
24917672 MGI
involved in cell adhesion IMP
IMP: 通过突变表型推断
24347169 MGI
involved in cellular hyperosmotic response IDA
IDA: 通过直接分析推断
37980412 MGI
involved in chemotaxis IDA
IDA: 通过直接分析推断
23142597 MGI
involved in cytolysis IDA
IDA: 通过直接分析推断
33472215 MGI
involved in ferroptosis IDA
IDA: 通过直接分析推断
38396301 MGI
involved in heterotypic cell-cell adhesion IMP
IMP: 通过突变表型推断
25766274 MGI
acts upstream of or within hyaloid vascular plexus regression IMP
IMP: 通过突变表型推断
19557008 MGI
involved in inflammatory response IMP
IMP: 通过突变表型推断
24347169 MGI
involved in leukocyte chemotaxis involved in inflammatory response IDA
IDA: 通过直接分析推断
24917672 MGI
involved in leukocyte chemotaxis involved in inflammatory response IMP
IMP: 通过突变表型推断
30510259 MGI
involved in macrophage chemotaxis IDA
IDA: 通过直接分析推断
24917672 MGI
involved in muscle cell differentiation IMP
IMP: 通过突变表型推断
31091274 MGI
involved in pericyte cell migration IMP
IMP: 通过突变表型推断
25766274 MGI
acts upstream of or within positive regulation of cell-matrix adhesion IMP
IMP: 通过突变表型推断
19557008 MGI
involved in positive regulation of inflammatory response IDA
IDA: 通过直接分析推断
26677008 MGI
involved in positive regulation of osteoclast development IMP
IMP: 通过突变表型推断
30700695 MGI
involved in positive regulation of toll-like receptor 4 signaling pathway IDA
IDA: 通过直接分析推断
25860173 MGI
involved in programmed necrotic cell death IDA
IDA: 通过直接分析推断
37980412 MGI
involved in protein homooligomerization IDA
IDA: 通过直接分析推断
24917672 MGI
involved in pyroptotic cell death IDA
IDA: 通过直接分析推断
36468682 MGI
involved in regulation of angiogenesis IMP
IMP: 通过突变表型推断
25766274 MGI
involved in regulation of monocyte chemotaxis IMP
IMP: 通过突变表型推断
32883094 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
23142597 MGI
located in filopodium membrane IDA
IDA: 通过直接分析推断
24917672 MGI
is active in plasma membrane IDA
IDA: 通过直接分析推断
38396301 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
27815839 MGI
located in synaptic membrane IDA
IDA: 通过直接分析推断
27815839 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ninjurin-1

nerve injury-induced protein 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ninj1 NCBI NCBI:4814
Rattus norvegicus Ninj1 NCBI NCBI:25338