1. Gene
  2. Nppc - natriuretic peptide type C Gene

Nppc - natriuretic peptide type C Gene

种属: Mus musculus

同用名: CNP; lbab

基因 ID: 18159 | 基因类型: protein coding

关于 Nppc

功能概要

This gene encodes a member of the natriuretic peptide family. Natriuretic peptides are involved in the control of blood pressure, extracellular fluid volume and electrolyte homeostasis. The encoded protein also plays a role in sensory neuron bifurcation, and is a critical regulator of endochondral bone growth. The encoded protein is a ligand for the natriuretic peptide receptor B, and is synthesized as a preprohormone which is cleaved to produce a mature peptide. Mutations in this gene are associated with dwarfism resulting from impaired endochondral ossification. [provided by RefSeq, Apr 2011]

Nppc 基因产物(1)

mRNA Protein Name
NM_010933.5 NP_035063.1 C-type natriuretic peptide preproprotein
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables signaling receptor binding IDA
IDA: 通过直接分析推断
14514678 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in angiogenesis IMP
IMP: 通过突变表型推断
30586761 MGI
acts upstream of or within animal organ development IMP
IMP: 通过突变表型推断
17439653 MGI
involved in blood vessel remodeling IMP
IMP: 通过突变表型推断
30586761 MGI
involved in c-di-GMP signaling IDA
IDA: 通过直接分析推断
23127564 MGI
acts upstream of cGMP biosynthetic process IMP
IMP: 通过突变表型推断
11259675 MGI
involved in cellular response to glycoprotein IDA
IDA: 通过直接分析推断
22987720 MGI
involved in chromosome organization IMP
IMP: 通过突变表型推断
22696190 MGI
involved in cumulus cell differentiation IMP
IMP: 通过突变表型推断
22696190 MGI
involved in gastric emptying IDA
IDA: 通过直接分析推断
23127564 MGI
involved in growth plate cartilage chondrocyte differentiation IMP
IMP: 通过突变表型推断
11259675 MGI
involved in growth plate cartilage chondrocyte proliferation IMP
IMP: 通过突变表型推断
11259675 MGI
involved in intracellular calcium ion homeostasis IDA
IDA: 通过直接分析推断
28054671 MGI
acts upstream of meiotic cell cycle IMP
IMP: 通过突变表型推断
20947764 MGI
involved in meiotic cell cycle process involved in oocyte maturation IMP
IMP: 通过突变表型推断
22696190 MGI
involved in multicellular organismal locomotion IMP
IMP: 通过突变表型推断
29501420 MGI
acts upstream of or within negative regulation of meiotic cell cycle IMP
IMP: 通过突变表型推断
20947764 MGI
involved in negative regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
29501420 MGI
acts upstream of or within negative regulation of oocyte maturation IMP
IMP: 通过突变表型推断
20947764 MGI
involved in oocyte development IMP
IMP: 通过突变表型推断
22696190 MGI
involved in ovarian follicle development IMP
IMP: 通过突变表型推断
22696190 MGI
acts upstream of or within post-embryonic development IMP
IMP: 通过突变表型推断
17439653 MGI
acts upstream of or within regulation of multicellular organism growth IMP
IMP: 通过突变表型推断
17439653 MGI
acts upstream of or within reproductive process IMP
IMP: 通过突变表型推断
20947764 MGI
involved in response to axon injury IMP
IMP: 通过突变表型推断
29501420 MGI
involved in response to decreased oxygen levels IMP
IMP: 通过突变表型推断
29501420 MGI
involved in response to ischemia IMP
IMP: 通过突变表型推断
30586761 MGI
involved in response to oxygen-glucose deprivation IMP
IMP: 通过突变表型推断
29501420 MGI
involved in response to wounding IMP
IMP: 通过突变表型推断
29501420 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

C-type natriuretic peptide

natriuretic peptide precursor C

natriuretic peptide precursor type C

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nppc NCBI NCBI:4880