2. Gene
  3. Nrxn2 - neurexin II Gene

Nrxn2 - neurexin II Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: mKIAA0921; 6430591O13Rik

基因 ID: 18190 | 基因类型: protein coding

关于 Nrxn2

功能概要

Enables several functions, including Calcium Channel regulator activity; cell adhesion molecule binding activity; and neuroligin family protein binding activity. Involved in postsynapse organization and signal transduction. Acts upstream of or within neurotransmitter secretion and synapse assembly. Part of protein-containing complex. Is expressed in several structures, including blood vessel; nervous system; and retina. Used to study autism spectrum disorder. Orthologous to human NRXN2 (neurexin 2). [provided by Alliance of Genome Resources, Apr 2022]

Nrxn2 基因产物(4)

mRNA Protein Name
NM_001205234.2 NP_001192163.1 neurexin-2 isoform 1 precursor
NM_001205235.2 NP_001192164.1 neurexin-2 isoform 3 precursor
NM_001369363.1 NP_001356292.1 neurexin-2 isoform 4 precursor
NM_020253.4 NP_064649.2 neurexin-2 isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium channel regulator activity IGI
IGI: 通过遗传相互作用推断
12827191 MGI
enables cell adhesion molecule binding IPI
IPI: 通过物理相互作用推断
21424692 MGI
enables neuroligin family protein binding IPI
IPI: 通过物理相互作用推断
21424692 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21356198 MGI
enables transmembrane signaling receptor activity IDA
IDA: 通过直接分析推断
21424692 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within chemical synaptic transmission IGI
IGI: 通过遗传相互作用推断
12827191 MGI
involved in gephyrin clustering involved in postsynaptic density assembly IDA
IDA: 通过直接分析推断
21424692 MGI
involved in neuroligin clustering involved in postsynaptic membrane assembly IDA
IDA: 通过直接分析推断
21424692 MGI
acts upstream of or within neurotransmitter secretion IGI
IGI: 通过遗传相互作用推断
12827191 MGI
involved in postsynaptic density protein 95 clustering IDA
IDA: 通过直接分析推断
21424692 MGI
involved in postsynaptic membrane assembly IDA
IDA: 通过直接分析推断
21424692 MGI
involved in presynaptic modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
36608123 MGI
involved in presynaptic modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
36608123 MGI
involved in regulation of postsynapse assembly IDA
IDA: 通过直接分析推断
36608123 MGI
involved in regulation of postsynapse assembly IMP
IMP: 通过突变表型推断
36608123 MGI
involved in regulation of postsynaptic neurotransmitter receptor activity IDA
IDA: 通过直接分析推断
25745399 MGI
involved in regulation of postsynaptic neurotransmitter receptor activity IMP
IMP: 通过突变表型推断
25745399 MGI
involved in signal transduction IDA
IDA: 通过直接分析推断
21424692 MGI
acts upstream of or within synapse assembly IGI
IGI: 通过遗传相互作用推断
12827191 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
25745399 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
25745399 MGI
part of protein-containing complex IPI
IPI: 通过物理相互作用推断
24613359 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neurexin-2

neurexin II alpha

neurexin II beta

neurexin-2-alpha

neurexin-2-beta

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09584 NRXN2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS21670 Nrxn2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS28188 Nrxn2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nrxn2 NCBI NCBI:9379
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