1. Gene
  2. Numbl - numb-like Gene

Numbl - numb-like Gene

种属: Mus musculus

同用名: nbl

基因 ID: 18223 | 基因类型: protein coding

关于 Numbl

功能概要

Involved in lateral ventricle development; neuroblast division in subventricular zone; and positive regulation of neurogenesis. Acts upstream of or within adherens junction organization and nervous system development. Located in cytoplasm. Is expressed in several structures, including central nervous system; peripheral nervous system ganglion; sensory organ; testis; and thymus. Orthologous to human NUMBL (NUMB like endocytic adaptor protein). [provided by Alliance of Genome Resources, Apr 2022]

Numbl 基因产物(1)

mRNA Protein Name
NM_010950.2 NP_035080.2 numb-like protein
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within adherens junction organization IGI
IGI: 通过遗传相互作用推断
17589506 MGI
acts upstream of or within axonogenesis IMP
IMP: 通过突变表型推断
15598981 MGI
acts upstream of or within forebrain development IMP
IMP: 通过突变表型推断
14687546 MGI
involved in lateral ventricle development IMP
IMP: 通过突变表型推断
17174898 MGI
acts upstream of or within nervous system development IMP
IMP: 通过突变表型推断
14687546 MGI
involved in neuroblast division in subventricular zone IMP
IMP: 通过突变表型推断
17174898 MGI
acts upstream of or within neuroblast proliferation IGI
IGI: 通过遗传相互作用推断
12410312 MGI
involved in positive regulation of neurogenesis IMP
IMP: 通过突变表型推断
12410312 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
9169836 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

numb-like protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Numbl NCBI NCBI:9253