2. Gene
  3. Ocln - occludin Gene

Ocln - occludin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ocl

基因 ID: 18260 | 基因类型: protein coding

关于 Ocln

功能概要

Predicted to enable protein domain specific binding activity. Involved in negative regulation of gene expression and tight junction organization. Located in several cellular components, including apical plasma membrane; apicolateral plasma membrane; and bicellular tight junction. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Crohn's disease and pseudo-TORCH syndrome 1. Orthologous to human OCLN (occludin). [provided by Alliance of Genome Resources, Apr 2022]

Ocln 基因产物(5)

mRNA Protein Name
NM_001360536.1 NP_001347465.1 occludin isoform 1
NM_001360537.1 NP_001347466.1 occludin isoform 1
NM_001360538.1 NP_001347467.1 occludin isoform 1
NM_001360539.1 NP_001347468.1 occludin isoform 2
NM_008756.2 NP_032782.1 occludin isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11782481 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of gene expression IMP
IMP: 通过突变表型推断
21415414 MGI
involved in tight junction organization IMP
IMP: 通过突变表型推断
30734065 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
20089884 MGI
located in apicolateral plasma membrane IDA
IDA: 通过直接分析推断
16520537 MGI
located in bicellular tight junction IDA
IDA: 通过直接分析推断
11025210 MGI
located in cell-cell junction IDA
IDA: 通过直接分析推断
12734665 MGI
located in endocytic vesicle IDA
IDA: 通过直接分析推断
15528189 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
11782481 MGI
located in tight junction IDA
IDA: 通过直接分析推断
23239027 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

occludin

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09743 OCLN Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22265 Ocln Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28788 Ocln Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ocln NCBI NCBI:100506658
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