2. Gene
  3. Pax8 - paired box 8 Gene

Pax8 - paired box 8 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Pax-8

基因 ID: 18510 | 基因类型: protein coding

关于 Pax8

功能概要

This gene encodes a member of a family of transcription factors that contain a characteristic N-terminal paired DNA-binding domain. The encoded protein is important for proper differentiation of the thyroid and the kidney. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Mar 2013]

Pax8 基因产物(1)

mRNA Protein Name
NM_011040.4 NP_035170.1 paired box protein Pax-8
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12441357 MGI
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
17047028 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in S-shaped body morphogenesis IEP
IEP: 通过表达模式推断
1723950 MGI
involved in central nervous system development IEP
IEP: 通过表达模式推断
1723950 MGI
acts upstream of or within epithelial cell differentiation IMP
IMP: 通过突变表型推断
9590297 MGI
involved in inner ear morphogenesis IGI
IGI: 通过遗传相互作用推断
20727173 MGI
involved in kidney epithelium development IEP
IEP: 通过表达模式推断
1723950 MGI
involved in mesonephric tubule development IEP
IEP: 通过表达模式推断
1723950 MGI
involved in mesonephros development IEP
IEP: 通过表达模式推断
1723950 MGI
involved in mesonephros development IMP
IMP: 通过突变表型推断
12435636 MGI
involved in metanephric distal convoluted tubule development IMP
IMP: 通过突变表型推断
17314325 MGI
involved in metanephric nephron tubule formation IMP
IMP: 通过突变表型推断
17314325 MGI
involved in metanephros development IEP
IEP: 通过表达模式推断
1723950 MGI
acts upstream of or within metanephros development IGI
IGI: 通过遗传相互作用推断
12435636 MGI
involved in negative regulation of apoptotic process involved in metanephric collecting duct development IMP
IMP: 通过突变表型推断
17314325 MGI
involved in negative regulation of apoptotic process involved in metanephric nephron tubule development IMP
IMP: 通过突变表型推断
17314325 MGI
involved in negative regulation of cardiac muscle cell apoptotic process IMP
IMP: 通过突变表型推断
22453009 MGI
involved in negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis IMP
IMP: 通过突变表型推断
17314325 MGI
involved in negative regulation of mesenchymal cell apoptotic process involved in metanephros development IMP
IMP: 通过突变表型推断
17314325 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
8413205 MGI
involved in positive regulation of DNA-templated transcription IGI
IGI: 通过遗传相互作用推断
16319112 MGI
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
12435636 MGI
involved in positive regulation of branching involved in ureteric bud morphogenesis IMP
IMP: 通过突变表型推断
17314325 MGI
involved in positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis IMP
IMP: 通过突变表型推断
12435636 MGI
involved in positive regulation of metanephric DCT cell differentiation IMP
IMP: 通过突变表型推断
17314325 MGI
involved in positive regulation of thyroid hormone generation IMP
IMP: 通过突变表型推断
12586753 MGI
involved in pronephric field specification IEP
IEP: 通过表达模式推断
12435636 MGI
involved in pronephros development IMP
IMP: 通过突变表型推断
12435636 MGI
involved in regulation of apoptotic process IMP
IMP: 通过突变表型推断
12435636 MGI
involved in regulation of metanephric nephron tubule epithelial cell differentiation IMP
IMP: 通过突变表型推断
17314325 MGI
involved in thyroid gland development IEP
IEP: 通过表达模式推断
1723950 MGI
acts upstream of or within thyroid gland development IGI
IGI: 通过遗传相互作用推断
11773436 MGI
acts upstream of or within thyroid gland development IMP
IMP: 通过突变表型推断
9590297 MGI
involved in urogenital system development IGI
IGI: 通过遗传相互作用推断
12435636 MGI
involved in ventricular septum development IMP
IMP: 通过突变表型推断
22453009 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
19010321 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

paired box protein Pax-8

paired box gene 8

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10095 PAX8 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-174555 Human PAX8 mRNA / 否
HY-RS18962 Pax8 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25453 Pax8 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pax8 NCBI NCBI:7849
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